Published on: 2025-06-30 | Written by: Prof. Dr. Basem Adel Ramadan, Professor of Cardiothoracic Surgery
Professor Dr. Bassem Adel Ramadan, Professor of Cardiothoracic Surgery at the Faculty of Medicine – Alexandria University, explains in this article the conditions that require surgical intervention for mitral valve disease, the difference between valve repair and replacement, and the latest techniques used to ensure the highest success rates.
The mitral valve is located between the left atrium and left ventricle of the heart. It controls one-way blood flow within the heart.
According to Professor Dr. Bassem Adel Ramadan, any malfunction in this valve can lead to reduced cardiac efficiency, fatigue, and shortness of breath.
Mitral Regurgitation:
Occurs when the valve doesn't close tightly, causing blood to flow backward into the atrium.
Mitral Stenosis:
Usually due to old rheumatic fever, it causes narrowing of the valve and impedes blood flow.
Infective Endocarditis:
A bacterial infection that damages valve tissue and often requires urgent surgery.
Congenital defects or rupture of valve leaflets or chords.
Professor Dr. Bassem Adel Ramadan notes that surgery becomes necessary in cases of:
Severe symptoms, such as shortness of breath and fatigue
Reduced left ventricular function (ejection fraction < 60%)
Pulmonary hypertension or heart enlargement
Failure of medication to manage symptoms
According to Professor Dr. Bassem Adel Ramadan, valve repair is generally preferred when feasible because:
It preserves the native heart structure
It does not require lifelong anticoagulation
It offers long-term durability
Valve replacement becomes necessary when the valve is too damaged. Options include:
Mechanical valves: long-lasting but require lifelong anticoagulants
Biological valves: no lifelong anticoagulation, but shorter lifespan (10–15 years)
As explained by Professor Dr. Bassem Adel Ramadan, recent advancements include:
Minimally invasive surgery with smaller incisions
Video-assisted mitral valve surgery (in selected cases)
Advanced myocardial protection during surgery
Use of high-quality, internationally certified valve prostheses
Mitral valve surgery is a precise, life-improving procedure when performed at the right time and by an experienced surgical team. Professor Dr. Bassem Adel Ramadan emphasizes the importance of early diagnosis and regular monitoring of heart function. With today's advanced techniques and intensive care protocols, surgical outcomes have become safer and more effective, allowing patients to return to a normal life more quickly.