Published on: 2025-06-23 | Written by: Dr. Mohamed Mustafa El Shazly, Consultant and Lecturer of Hematology
Dr. Mohamed Mostafa El Shazly, Consultant in Hematology and Specialist in Diagnosing Bleeding and Clotting Disorders, clarifies that a low platelet count isn’t always a medical emergency—but in some cases, it may signal a serious condition that requires urgent attention. So, what is thrombocytopenia (low platelets), when is it harmless or temporary, and when should you see a doctor?
In this article, Dr. Mohamed Mostafa El Shazly explains the difference between benign and serious causes of low platelet count, and how proper diagnosis and treatment are essential.
Platelets are blood components responsible for clotting and stopping bleeding. A normal platelet count ranges from 150,000 to 450,000 per microliter of blood.
A significant drop in platelet levels may increase the risk of bleeding—either external (easy bruising) or internal (gum bleeding, nosebleeds, or even organ-related bleeding).
According to Dr. Mohamed Mostafa El Shazly, there are many situations in which thrombocytopenia is mild, temporary, and not a cause for concern, such as:
After a minor viral infection (e.g., influenza or dengue)
During pregnancy, especially in the third trimester
As a side effect of certain medications
In mild autoimmune cases that respond well to treatment
In these scenarios, the person may have no symptoms, and the low count might be discovered by chance during routine blood work.
In some cases, a low platelet count is a warning sign of a more serious illness, such as:
Autoimmune diseases (like ITP – Immune Thrombocytopenia)
Certain types of blood cancer (e.g., leukemia)
Chronic viral infections (like hepatitis C or HIV)
Bone marrow failure or rare inherited disorders
Dr. Mohamed Mostafa El Shazly emphasizes that symptoms like frequent bleeding, red pinpoint spots on the skin (petechiae), or blood in urine or stool should not be ignored.
Diagnosis includes:
Complete Blood Count (CBC)
Further testing to determine the cause (immune-related? viral? bone marrow issue?)
Bone marrow biopsy if necessary
Dr. Mohamed Mostafa El Shazly stresses the importance of accurate diagnosis to guide the proper treatment plan, as it may vary significantly depending on the underlying cause.
Treatment depends on the cause:
For mild cases: monitoring only
For immune-related cases: corticosteroids or immunosuppressants
For active bleeding: platelet transfusions
For chronic or malignant conditions: treating the underlying disease
Not all cases of thrombocytopenia are dangerous, but early diagnosis helps distinguish between mild conditions and those needing immediate intervention. Dr. Mohamed Mostafa El Shazly recommends regular blood testing and urges patients not to ignore symptoms that might indicate a clotting disorder or significant platelet drop.