

Neurodermatitis (Lichen Simplex Chronicus) is one of the most common skin problems affecting both children and adults. It causes intense itching and persistent skin irritation. This condition is not only physically uncomfortable but can also affect sleep, mood, and self-confidence.
In this Dalily Medical article, we will discuss:
The causes of neurodermatitis
Key symptoms you should be aware of
Its different types
The most effective treatment options for both children and adults
You will also find important tips on managing the condition and reducing irritation, helping you maintain healthy and comfortable skin.
What is Neurodermatitis?
Neurodermatitis (Lichen Simplex Chronicus) is a chronic skin condition that causes severe itching and sores due to constant scratching. It often appears on the hands, feet, neck, and scalp and can significantly disrupt daily life.
Are children at risk?
Yes, children can develop neurodermatitis, especially if their skin is dry or exposed to allergens. In children, it usually appears on the face, behind the ears, or on the hands.
Are men more prone than women?
Overall, there’s no significant gender difference, but:
Men often develop it on the hands and beard area.
Women often develop it on the hands, arms, or face.
Does neurodermatitis affect sleep?
Yes, intense nighttime itching can disrupt sleep and increase stress, which in turn can worsen the symptoms.
Can neurodermatitis be completely cured?
There’s no permanent cure, but the condition is manageable. Medications and daily care can significantly reduce flare-ups and maintain healthy, comfortable skin.
Does stress cause or worsen neurodermatitis?
Stress is not the main cause but acts as a trigger, increasing itching, flaking, and inflammation.
Do children require different treatments than adults?
Yes, medications such as corticosteroids or antihistamines are adjusted based on age and weight. Daily moisturizing and skin care are also crucial for children.
Is neurodermatitis contagious?
No, it is not contagious. However, constant scratching can lead to secondary bacterial or fungal infections.
Does weather affect the condition?
Yes, cold and dry weather increases skin dryness and itching, while hot and humid weather can cause sweating and irritation.
Does diet affect neurodermatitis?
Some fatty, spicy, or allergenic foods may trigger symptoms in certain individuals, though effects vary from person to person.
Can you exercise with neurodermatitis?
Yes, but avoid excessive sweating or rough clothing, and cleanse and moisturize the skin immediately afterward.
Difference between neurodermatitis, seborrheic, and atopic eczema:
Neurodermatitis: Persistent itching and sores from scratching.
Seborrheic eczema: Related to oils and fungal activity.
Atopic eczema: Often hereditary, triggered by allergens.
Men:
Stress & psychological pressure: Work and life stress can trigger chronic itching.
Dry skin: Exposure to cold, hot water, or harsh soaps increases inflammation and itching.
Daily habits: Constant scratching due to stress or nervous habits worsens the condition.
Chronic health problems: Diabetes or thyroid disorders affect skin health.
Women:
Hormonal changes: Pregnancy, menstruation, or menopause increase skin sensitivity.
Stress & anxiety: Major factors in worsening itching.
Harsh skincare products: Strong creams or perfumes increase inflammation.
Natural skin dryness: Especially in winter or with aging.
Children:
Natural dry skin: Sensitive skin in newborns increases susceptibility.
Allergies: Food, detergents, or rough clothing may trigger itching.
Genetics: Family history of eczema, asthma, or allergies increases risk.
Stress or discomfort: Environmental changes or stress can cause chronic itching.
In Men:
Severe chronic itching on hands, arms, neck, or scalp
Thickened, hardened skin due to repeated scratching
Redness and irritation, worsened by stress
Flaking or small cracks
Dark spots or pigmentation from repeated scratching
In Women:
Continuous or intermittent itching on neck, hands, legs, or scalp
Thickened, wrinkled skin from chronic scratching
Redness and mild flaking under stress or harsh products
Dry, sensitive skin, especially in winter
Pigmentation or dark spots from scratching
In Children:
Severe nighttime itching disrupting sleep
Red or swollen patches on hands, feet, face, or behind ears
Dry, flaky skin
Thickened skin if prolonged
Irritability or behavioral issues due to chronic itching
Men:
Palmar Neurodermatitis: Chronic itching, thickened and cracked skin on hands
Cervical & Arm Neurodermatitis: Red patches, severe itching, flaking, often stress-related
Scalp Neurodermatitis: Scales, itching, occasional temporary hair loss
Women:
Facial Neurodermatitis: Itching, redness, dry skin on cheeks and forehead, often stress-related
Palmar Neurodermatitis: Dryness, cracks, chronic itching from household work
Cervical & Back Neurodermatitis: Red, hardened patches on neck or lower back, worsened by stress
Children:
Scalp Neurodermatitis: Often on the back or sides of the head, causing flakes, itching, redness
Hand & Foot Neurodermatitis: Flaking, cracks, severe nighttime itching
Facial & Neck Neurodermatitis: Common in infants, red, dry, sometimes with small blisters from scratching
Men:
Chronic itching and cracks causing secondary infections
Skin texture changes: thickened or rough skin
Bacterial and fungal infections through scratches
Psychological impact: stress and low self-confidence
Women:
Redness and skin cracks
Overly sensitive skin reacting to cosmetics or detergents
Psychological and social effects: anxiety and stress
Increased risk of infections from scratching
Children:
Severe itching and sleep disruption affecting growth and focus
Skin cracks and sores leading to infections
Higher susceptibility to bacterial/fungal infections
Psychological impact: irritability or behavioral issues
Slower healing in sensitive or immunocompromised children
Genetics: Family history of eczema, skin allergies, or asthma increases risk.
Stress: Psychological stress worsens itching and inflammation.
Environmental factors: Dry/cold weather, exposure to harsh chemicals, dust, or pollution triggers symptoms.
Poor skincare habits: Strong soaps, scented creams, and constant scratching increase irritation.
Medical conditions: Weak immunity, chronic skin diseases, or neurological/inflammatory disorders.
Child-specific factors: Synthetic or wool clothing, prolonged diaper use, or food allergies can increase flare-ups.
Area | Possible Causes | Common Symptoms | Complications | Treatment |
---|---|---|---|---|
Hands | Chemicals, frequent washing, stress | Severe itching, redness, dryness, flaking, cracks | Difficulty using hands, secondary infections | Moisturizers, anti-inflammatory creams, hand protection, sometimes topical corticosteroids |
Feet | Tight shoes, sweating, poor circulation | Itching, flaking, painful cracks | Difficulty walking, fungal infections | Antifungal creams, moisturizers, appropriate footwear |
Arms (wrists/elbows) | Friction, stress, sensitive skin | Thickened skin, redness, repeated itching | Skin thickening, small sores | Moisturizers, mild corticosteroids, avoid irritants |
Legs (knees/ankles) | Stress, dry skin, friction | Severe itching, thickened skin, small sores | Movement difficulty, infections | Continuous moisturizing, anti-inflammatory creams, avoid scratching |
Face (forehead/cheeks) | Stress, allergies, harsh cosmetics | Redness, flaking, itching | Low self-confidence, recurrent infections | Light moisturizers, anti-inflammatory creams, avoid harsh products |
Neck | Friction from clothes, stress, allergies | Itching, redness, hardened skin | Thickened skin, pigmentation | Moisturizers, mild corticosteroids, cotton clothing |
Back & Shoulders | Stress, friction, heat | Red patches, persistent itching | Chronic skin irritation | Anti-inflammatory creams, moisturizing, stress reduction |
Chest | Stress, allergies, friction | Redness, itching, small blisters | Chronic irritation, inflammation | Moisturizers, mild topical corticosteroids, avoid triggers |
Scalp | Excess oil, Malassezia, stress | Severe itching, scales, thickened skin | Temporary hair loss, infections | Medicated shampoos, antifungal creams, phototherapy or laser for severe cases |
Face around mouth/nose | Stress, skin irritation, spicy foods | Redness, flaking, itching | Skin pigmentation, infections | Moisturizers, avoid triggers, anti-inflammatory creams if needed |
Joints (elbows/knees) | Repeated friction, chronic scratching | Thickened skin, itching, cracks | Pain during movement, infections | Continuous moisturizing, mild corticosteroids, avoid scratching |
Fingers/whole hands | Water/chemical exposure, stress | Cracks, severe itching, dryness | Difficulty with daily tasks, secondary infections | Moisturizers, hand protection, anti-inflammatory creams when necessary |
General Tips for Preventing and Managing Neurodermatitis
Maintain consistent skin hydration: Use lightweight moisturizers suitable for sensitive skin to reduce dryness and itching.
Avoid scratching whenever possible: Scratching worsens inflammation and delays healing. Try gentle pressure or cold compresses to relieve itching.
Use moisturizers and topical anti-inflammatory creams as needed: Helps calm inflammation and reduce redness.
Avoid harsh chemicals and strong cosmetics: Choose fragrance-free and alcohol-free products.
Manage stress and practice relaxation techniques: Stress triggers itching and worsens symptoms; breathing exercises or yoga can help.
Topical corticosteroids
Adults: Mild creams such as Hydrocortisone 1% to reduce itching and redness. Short-term use under medical supervision.
Children: Very mild creams in smaller doses to avoid side effects on sensitive skin.
Moisturizers and skin soothers
Suitable for all ages to relieve dryness and itching.
Examples: Creams with Ceramides, Aloe Vera, or Colloidal Oatmeal.
Maintains hydration and strengthens the skin barrier.
Topical antifungals or antibiotics
Used if secondary bacterial or fungal infection occurs due to scratching.
Antihistamines
For adults and children to relieve severe itching, especially at night, improving sleep.
Examples: Cetirizine, Loratadine.
Oral corticosteroids
Short-term use for severe cases or acute flare-ups.
Must be prescribed and monitored by a doctor to avoid side effects.
Oral antibiotics
For secondary bacterial infections caused by excessive scratching.
Topical immunomodulators
Tacrolimus and Pimecrolimus for adults and older children to reduce prolonged corticosteroid use.
Oral immunosuppressants or biologics
For chronic or severe cases unresponsive to conventional therapy.
Requires careful supervision by a specialist.
Follow prescribed doses and duration carefully to avoid complications.
Always use moisturizers alongside medical creams to reduce dryness and irritation.
Avoid scratching to prevent worsening inflammation.
Regular follow-up for children is essential to adjust doses and protect sensitive skin.
Fractional Laser:
Adults: Improves skin texture and reduces thickness caused by chronic scratching.
Children: Rarely used, only in special cases under strict supervision.
Mechanism: Penetrates superficial skin layers, reduces thickness, stimulates cell regeneration, gradually reduces itching and redness.
Intense Pulsed Light (IPL):
Effective in reducing redness and pigmentation from chronic neurodermatitis.
Safe for adults and can be used cautiously in older children.
CO₂ Laser:
Used for chronic cases causing thickened skin or scars.
Recommended for adults under specialized supervision.
Improves skin regeneration and gives a smoother appearance.
Skin excision or surgical intervention:
Very rare; used only in chronic neurodermatitis with severe thickening or large scars affecting function or aesthetics.
Mostly for adults; children’s skin regenerates quickly and rarely requires surgery.
Post-surgery: Use moisturizers and anti-inflammatory creams to accelerate healing and prevent recurrence.
Important Notes for Laser or Surgery:
Always under the supervision of a dermatologist.
Use high SPF sunscreen after laser sessions to prevent pigmentation.
Skin needs time to recover; consistent use of moisturizers and soothing creams is essential.
Laser or surgery does not treat the root cause but improves skin appearance and reduces effects of chronic scratching.
1️⃣ Mild Neurodermatitis
Symptoms: Light itching, slight redness, small flakes
Management:
Use gentle daily moisturizers, fragrance-free
Avoid scratching
Bathe with lukewarm water, avoid harsh soaps
Wear soft cotton clothing to reduce friction
2️⃣ Moderate Neurodermatitis
Symptoms: Frequent itching, noticeable redness, larger flakes, localized thickened skin
Management:
Use topical anti-inflammatory creams as prescribed (mild corticosteroids)
Avoid stress triggers
Maintain daily hydration with Ceramides or Aloe Vera
Monitor for infection signs such as pus or odor, consult a doctor if needed
3️⃣ Severe or Chronic Neurodermatitis
Symptoms: Severe persistent itching, sores, pronounced redness and thickening, occasional bleeding or heavy flaking
Management:
Adhere to prescribed medications, including corticosteroids or antihistamines if necessary
Consider therapeutic sessions such as phototherapy or laser under doctor supervision
Avoid scratching strictly, use cold compresses
Follow a healthy diet rich in omega-3s and vitamins to support immunity
Regular follow-up with a dermatologist to adjust treatment
Bathe with lukewarm water using gentle children’s cleansers
Moisturize immediately after bathing to reduce dryness and itching
Keep nails trimmed to prevent scratching
Wear soft cotton clothing and change it daily
Avoid foods that may irritate the skin or trigger allergies
Men:
Pay attention to scalp and beard areas, common sites for neurodermatitis
Use lightweight, oil-free hair and facial products
Women:
Avoid harsh cosmetics or strong perfumes on affected areas
Maintain daily hydration and manage stress, which can worsen symptoms