Published on: 2025-06-12 | Written by: Professor Dr. Nasser Zahran, Consultant Neurologist
Peripheral neuropathy is one of the most common neurological disorders that significantly impact quality of life. It affects millions of people worldwide, with symptoms ranging from mild tingling to severe pain and motor impairment. In this article, Dr. Nasser Zahran, a consultant neurologist, explains the key causes of the condition, how it is diagnosed, and the latest treatment options available.
Peripheral neuropathy is a disorder that affects the peripheral nerves, which are responsible for transmitting signals between the central nervous system (the brain and spinal cord) and the rest of the body. It can lead to loss of sensation, muscle weakness, nerve pain, or balance issues.
Diabetes (the most common cause)
Vitamin deficiencies, especially Vitamin B12
Viral or bacterial infections affecting the nerves
Autoimmune diseases (e.g., lupus, Guillain-Barré syndrome)
Excessive alcohol consumption
Exposure to toxins or certain medications (e.g., chemotherapy)
Genetic disorders
Dr. Nasser Zahran highlights the importance of early diagnosis, as effective treatment begins with accurate evaluation, which includes:
Clinical neurological examination
Nerve conduction studies (NCS)
Electromyography (EMG)
Blood tests to check for diabetes, vitamin levels, liver and kidney function
MRI scans, when needed, to rule out central causes
Tingling or numbness in hands or feet
Burning or stabbing nerve pain
Muscle weakness or wasting
Loss of balance or coordination
Increased sensitivity to touch or pain
Such as tight blood sugar control in diabetic patients.
Antidepressants (e.g., duloxetine)
Anticonvulsants (e.g., gabapentin or pregabalin)
Neuropathic pain relievers
Improves muscle strength and balance
Reduces pain with targeted exercises
Helps relieve pain and enhance nerve function
Especially for cases caused by B12 or folate deficiency
Control chronic conditions like diabetes and hypertension
Avoid smoking and limit alcohol intake
Eat a balanced diet rich in vitamins
Exercise regularly
Schedule regular nerve checkups, especially for diabetics
“Peripheral neuropathy is not an inevitable fate—it can be managed and improved significantly with early diagnosis and a tailored treatment plan,” says Dr. Nasser Zahran.