Published on: 2025-06-18 | Written by: Dr. Menna Abdel Razek ElKhatib Specialist in Rheumatic
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs in the body. Its symptoms can be unpredictable and significantly impact quality of life. In this article, we explore the nature of the disease and modern treatment methods with Dr. Mona Abdel Razek El-Khatib, Assistant Professor of Rheumatology and Immunology, and how patients can manage it effectively.
Lupus is an autoimmune condition in which the immune system mistakenly attacks the body’s healthy tissues. This leads to chronic inflammation that can affect the skin, joints, kidneys, heart, lungs, and nervous system.
Dr. Mona Abdel Razek El-Khatib explains that lupus is more common in women, especially during childbearing years, and symptoms may develop gradually or appear suddenly.
Facial rash in the shape of a “butterfly”
Joint pain and stiffness
Hair loss
Unexplained fever
Constant fatigue
Mouth ulcers
Kidney or heart issues in advanced cases
According to Dr. Mona Abdel Razek El-Khatib, diagnosis involves combining clinical symptoms with specific blood tests, such as:
ANA (Antinuclear Antibodies)
Anti-dsDNA
Kidney function and complete blood count tests
Diagnosis is based on the presence of several internationally recognized criteria.
The treatment focuses on reducing immune system activity, managing symptoms, and preventing complications. Options include:
NSAIDs for pain and inflammation
Corticosteroids in controlled doses
Immunosuppressive medications like hydroxychloroquine
Treatments for associated symptoms, such as anemia or kidney inflammation
Dr. Mona Abdel Razek El-Khatib emphasizes the importance of regular monitoring and adjusting medications based on disease activity.
Get adequate rest and avoid overexertion
Maintain a balanced and nutritious diet
Avoid direct sunlight exposure
Seek psychological support and stay in regular contact with your doctor
Stick to medications, even during remission
As Dr. Mona Abdel Razek El-Khatib states: “Lupus is a chronic disease, but it's not the end – awareness is the first step toward controlling it.”
If you frequently experience the above symptoms or notice unexplained changes in your health, consulting a rheumatology and immunology specialist like Dr. Mona Abdel Razek El-Khatib is crucial for timely diagnosis and intervention.