Spinal cord cancer is a rare and serious condition that affects the spinal cord. It occurs when abnormal cells grow inside or around the spinal cord, putting pressure on the nerves and causing uncomfortable symptoms such as pain, muscle weakness, or problems controlling bladder and bowel function. Early detection of the tumor increases the chances of successful treatment and reduces complications. That’s why it’s important to understand how spinal cord cancer develops, its early signs, and the latest available treatments article, we’ll cover all the essential details: the causes of spinal cord cancer, its symptoms, tumor stages, diagnosis, treatment options, and important information on prevention and early detection, explained in a simple and easy-to-understand way.
Spinal cord cancer occurs when abnormal cells grow inside or around the spinal cord, putting pressure on the nerves and causing symptoms such as:
Persistent pain in the back or neck
Muscle weakness or numbness
Problems controlling bladder or bowel function
Spinal cord tumors start when genetic mutations occur in spinal cord cells or surrounding tissues. These mutations disrupt the normal mechanisms that control cell growth and division, causing the affected cells to grow abnormally and form a mass or tumor.
Tumors can originate from different types of cells:
Neurons or glial cells within the spinal cord → Intramedullary tumors
Meningeal cells from the protective layers → Intradural-Extramedullary tumors
Bone and soft tissue cells surrounding the spinal cord → Extradural tumors
No, spinal cord tumors are not contagious. However, they may be associated with genetic or health factors that increase the risk of developing the condition.
There is no fixed number, as survival depends on the tumor type and stage at diagnosis. Early detection and appropriate treatment can result in a 5-year survival rate close to 100%. Advanced stages or malignant tumors reduce the chances of recovery and increase the risk of complications.
Spinal cord cancer can cause:
Difficulty moving
Pain while walking or performing daily activities
After treatment or surgery, most patients gradually return to normal life with rehabilitation and medical support.
Yes, most tumors occur in adults over 40, but children can also be affected, especially in malignant or lymphatic tumors.
Pressure on nerves may cause:
Numbness or tingling in the limbs
Loss of sensation in certain areas
Muscle weakness
No, small or benign tumors may be managed with observation, radiation, or chemotherapy depending on the tumor’s size and location.
Yes, especially malignant or advanced tumors, which makes regular medical follow-up essential to prevent recurrence.
Spinal cord tumors may temporarily affect sexual function if nerves responsible for reproductive function are involved. However, most patients recover gradually after treatment.
Healthy nutrition supports the body during treatment of spinal cord tumors:
Strengthens the immune system
Helps tolerate chemotherapy or radiation therapy
Recommended foods:
Healthy proteins
Fresh vegetables and fruits
Adequate water intake
Nutrition does not prevent the tumor directly but helps the body cope with treatment.
Yes, although it is very rare. Pediatric cases are usually malignant or hereditary, requiring close monitoring by a specialized medical team.
Spinal cord tumors can be benign or malignant, and causes vary by tumor type and location. Scientists have not identified a single cause for all tumors, but several risk factors are known:
Genetic mutations: Changes in DNA of neurons or surrounding tissues can cause abnormal cell growth. Some mutations are inherited, while others occur randomly over time.
Secondary (Metastatic) tumors: Cancer from another part of the body, such as breast, lung, or prostate, may spread to the spinal cord.
Radiation exposure: Prolonged exposure to high doses of radiation or previous radiation therapy to the back can increase the risk of spinal cord tumors.
Rare genetic disorders: Certain syndromes increase the risk of nervous system tumors, such as:
Neurofibromatosis type 1 and 2
Von Hippel-Lindau syndrome
Age and gender: Most tumors occur in adults aged 30–60. Some types are more common in men or women depending on tumor type.
Other possible factors: Chronic immune deficiency or exposure to harmful chemicals may increase the risk of abnormal cell growth in the spinal cord.
Spinal cord tumors are classified based on their location relative to the spinal cord and their cell of origin. Generally, there are three main types:
These tumors arise within the spinal cord itself, often from glial cells.
Most affected area: Cervical (neck) region
Common types:
Ependymoma: Most common spinal cord tumor in adults; arises from ependymal cells lining the central canal of the spinal cord.
Astrocytomas: More common in children; develop from astrocytes (star-shaped glial cells) and can be low-grade or highly malignant.
Symptoms:
Early sensory disturbances
Motor weakness due to the central location in the spinal cord
These tumors grow inside the dura mater (tough outer membrane) but outside the spinal cord itself. They usually compress the spinal cord from the outside and are often benign.
Common types:
Meningiomas: Arise from the meninges, slow-growing, more common in middle-aged women.
Schwannomas & Neurofibromas: Originate from nerve root sheaths, can be associated with neurofibromatosis, causing nerve compression.
Symptoms:
Localized pain
Weakness or numbness due to nerve compression
These occur outside the dura mater, often in the vertebrae or surrounding soft tissues.
Common types:
Metastatic tumors: Spread from other cancers such as breast, prostate, or lung.
Primary bone tumors: Such as bone sarcomas or vertebral tumors, though rare.
Symptoms:
Back pain
Neurological deficits due to spinal cord compression
The stage of a spinal cord tumor depends on its size, location, and extent of spread, which guides treatment and prognosis.
Description: Small tumor confined within or around the spinal cord
Symptoms: Mild, such as slight pain or mild numbness in limbs
Treatment: Usually surgery or focused radiation
Recovery: Very high if detected early
Description: Larger tumor confined to the spinal canal or surrounding area
Symptoms: May press on nerves, causing:
Muscle weakness
Difficulty moving
Bladder or bowel control problems
Treatment: Surgery with radiation or chemotherapy depending on tumor type
Description: Tumor begins to invade surrounding tissue or nearby bones
Symptoms: More severe:
Persistent pain
Numbness or loss of sensation
Significant limb weakness
Treatment: Extensive surgery + radiation, sometimes chemotherapy
Description: Tumor has spread to distant organs, other parts of the nervous system, or is secondary from another cancer
Symptoms: Severe, including:
Partial or complete paralysis
Loss of control over vital functions
Severe pain and systemic complications
Treatment: Focused on symptom management and quality of life:
Radiation or chemotherapy
Immunotherapy or targeted therapy in some cases
Psychological and nutritional support
Spinal cord tumors can affect not only the spinal cord but also the nervous system and overall body function. Complications vary depending on tumor type, size, location, and stage.
Spinal Cord Compression
Symptoms: Weakness or numbness in limbs, difficulty walking or balancing, severe back or neck pain
Loss of Sensation and Muscle Control
Pressure on nerves can cause:
Loss of sensation in hands or feet
Muscle weakness or partial paralysis
Difficulty controlling bladder or bowel
Chronic Pain
Caused by tumor pressure on nerves or inflammation of surrounding tissues
Impacts sleep, mobility, and daily activities
Spinal and Bone Problems
Some tumors spread to vertebrae or surrounding bones, causing:
Fractures
Deformities or spinal curvature
Increased risk of spinal cord compression
Spread to Other Parts of the Body
Malignant tumors may metastasize to:
Brain
Lungs or liver (in secondary tumors)
Treatment-Related Complications
Chemotherapy & radiation: Weakened immunity, nausea, vomiting, hair loss, skin or mucous irritation
Temporary or permanent muscle weakness
Problems with movement or sensation control
Patients may experience:
Depression and anxiety due to pain and loss of mobility
Difficulty performing daily activities or work
Feelings of isolation or low self-confidence
Symptoms of spinal cord tumors can appear gradually or suddenly depending on tumor size, location, and growth rate. Most are related to pressure on the spinal cord or surrounding nerves.
Back or Neck Pain
Most common symptom, can be constant or intermittent
Worsens with movement, coughing, or sneezing
Often the first sign before other symptoms appear
Weakness or Numbness in Limbs
Weakness in arms or legs depending on tumor location
Tingling, numbness, or “pins and needles” sensation
May cause difficulty walking or loss of balance
Bladder or Bowel Control Problems
Urinary or fecal incontinence
Difficulty urinating or passing stool
Caused by tumor pressing on nerves controlling these functions
Stiffness or Loss of Mobility
Muscle stiffness or difficulty moving limbs
In advanced cases, partial or complete paralysis may occur
Sensory Loss and Balance Issues
Loss of ability to feel temperature, touch, or pain in certain areas
Difficulty maintaining balance while standing or walking
General Symptoms
Headache or dizziness (especially in upper neck or spinal tumors)
Extreme fatigue or unexplained weight loss
Sometimes nausea or vomiting if tumor compresses upper nerves
Accurate diagnosis is essential because symptoms can mimic herniated discs, nerve inflammation, or spinal canal narrowing. A combination of tests is used to confirm diagnosis and stage the tumor.
Clinical Examination & Medical History
Discuss symptoms: neck/back pain, limb weakness/numbness, walking difficulty, bladder/bowel issues
Physical exam: muscle strength, reflexes, sensation, and balance
Imaging Studies
MRI: Best for locating the tumor, measuring size, and evaluating relationship with spinal cord and nerves; crucial for surgical planning
CT Scan: Assesses surrounding bones, useful if tumor involves vertebrae
PET Scan: Shows activity of cancerous cells, used for malignant or metastatic tumors
Biopsy
Tissue sample taken for microscopic analysis
Determines tumor type (benign or malignant)
Evaluates growth rate and spread to choose optimal treatment
Neurological Tests
Assess muscle strength and reflexes
Test sensation and balance
Determine tumor impact on the nervous system
Blood Tests and General Health
Liver and kidney function
Complete blood count (CBC)
Inflammatory markers or secondary tumor indicators
Additional Tests if Needed
Viral or immune-related tests
Immune system evaluation, especially in patients with chronic disease or prior chemotherapy
Treatment depends on: tumor type (benign or malignant), location, size, stage, and overall health. The main goals are to relieve spinal cord pressure, reduce pain, and prevent tumor spread.
Surgery
Primary treatment for most spinal cord tumors, especially localized ones
Goal: Remove the tumor fully or partially to relieve pressure
Types of surgery:
Local excision (Laminectomy & Tumor Excision): Remove tumor while preserving spine structure
Extensive removal with spinal fusion: For large tumors or those affecting vertebrae
Post-surgery rehabilitation is usually needed to improve mobility and strengthen muscles
Radiation Therapy
Uses high-energy rays to destroy cancer cells
Types:
External Beam Radiation: Most common, focused on tumor
Stereotactic Radiosurgery (SRS): Highly precise for small or difficult-to-reach tumors
Goals: Reduce tumor size, prevent spread, relieve pain in advanced cases
Chemotherapy
Kills or stops growth of cancer cells, often for malignant or metastatic tumors
Common drugs: Temozolomide, Cisplatin, Carboplatin
Can be used alone or with radiation depending on patient condition
Immunotherapy
Stimulates the immune system to attack cancer cells
Used for rare tumors or those resistant to conventional treatments
Sometimes combined with chemotherapy or radiation for increased effectiveness
Targeted Therapy
Used if specific genetic mutations or proteins are present
Targets cancer cells precisely with minimal effect on healthy cells
Example: Drugs targeting EGFR or VEGF
Palliative & Supportive Care
Focuses on improving quality of life, especially in advanced or inoperable tumors
Includes:
Pain management
Treatment of infections or neurological complications
Psychological and nutritional support
Muscle and mobility rehabilitation
While spinal cord tumors cannot always be prevented, especially if genetic or unknown, there are steps to reduce risk or detect them early:
Genetic Health Monitoring
If there’s a family history of spinal or brain tumors, consult a specialist
Some genetic mutations increase risk; early testing helps with prevention or early detection
Early Detection & Regular Checkups
Persistent neck/back pain with limb numbness or weakness should prompt a neurologist visit
Early diagnosis improves treatment success and reduces complications
Avoid Excessive Radiation Exposure
Long-term exposure without protection can increase tumor risk
Use protective measures if undergoing imaging or radiation therapy
Maintain Strong Immune System
Adequate sleep, balanced nutrition, regular exercise
Avoid smoking and excessive alcohol
Manage Chronic Diseases
Conditions like diabetes or autoimmune disorders may affect the nervous system
Proper treatment and monitoring reduce complications that can facilitate tumor growth
Pay Attention to Early Symptoms
Persistent pain or numbness in limbs
Muscle weakness or difficulty walking
Bladder or bowel control problems
Loss of balanc
Any of these signs should prompt immediate medical evaluation for early detection