Oxosomes for treating hair loss key benefits side effects and tips

Recently, a new treatment has emerged and become popular among cosmetic experts for treating hair loss: Exosome injections. This technique relies on powerful growth factors derived from stem cells, which work to regenerate hair follicles from within, strengthen them, and stimulate faster new hair growth compared to traditional treatments.Because of this, many people ask Dalily Medical Is exosome therapy really better than PRP (platelet-rich plasma)? Are there any side effects? And what should I do before and after the sessions to maintain the results?

Is Exosome Therapy Suitable for All Types of Hair Loss?
Exosome treatment is most effective for mild to moderate hair thinning and is also highly beneficial for hereditary hair thinning in both men and women. However, in cases of complete or advanced baldness, exosome therapy alone may not be sufficient, and additional solutions such as hair transplantation might be necessary.

When Do Exosome Injection Results Appear?
Results are not immediate:

• Initial improvement usually begins 6–8 weeks after the first session.

• Final results typically appear within 3–6 months, as hair follicles need time to re-enter the growth phase.

Is the Exosome Session Painful?
Pain is minimal. Most patients only feel a slight tingling or pinprick sensation. Clinics usually apply a topical numbing cream before the session to reduce discomfort.

Can I Dye My Hair After Exosome Therapy?
It is recommended to wait at least 4 weeks before coloring or chemically straightening the hair, as harsh chemicals can irritate the scalp and reduce the treatment’s effectiveness.

Can PRP Be Combined with Exosomes?
Yes. Many people combine PRP (Platelet-Rich Plasma) with exosomes because PRP strengthens hair follicles while exosomes stimulate cellular regeneration. This combination often produces faster and stronger results, especially for hereditary hair loss.

Are There Serious Side Effects of Exosome Hair Injections?
Exosome therapy is considered very safe, with minimal risk of serious side effects since it is derived from safe, body-compatible or closely related sources. Minor temporary side effects may include:

• Mild redness

• Slight swelling at the injection site

These typically resolve quickly.

How Many Sessions Are Required for Optimal Results?
The number of sessions depends on individual scalp condition and response, but on average:

• 5–8 sessions are recommended.

• Sessions are spaced 3–6 months apart, depending on the doctor’s plan.

When Will I See Results from Exosome Therapy?

• Some improvement may be noticed after the second session.

• Gradual improvements continue with each session.

• Final results usually appear after about 1 year, with reduced hair shedding and increased hair density.

Is Exosome Therapy Permanent?
The longevity of results depends on:

• Individual response

• The expertise of the physician performing the procedure

• Post-treatment hair care

With proper maintenance, results can be long-lasting.

Is Exosome Therapy a Substitute for Hair Transplantation?
Exosomes are not a direct replacement for hair transplants. They can:

• Strengthen existing hair

• Reduce hair loss

• Stimulate new follicle growth

However, for completely bald areas, a hair transplant may still be necessary.

Duration of Exosome Hair Therapy
Exosome therapy is not a single-session treatment. Most patients require 5 or more sessions, with the first 2–3 sessions initiating follicle stimulation. Subsequent sessions gradually improve hair density.

Gradual Results

• Hair density, follicle health, and reduced shedding improve over time.

• Most patients notice significant improvement after consistent sessions.

• Maintenance sessions may be recommended periodically to sustain results.

Exosome Therapy Requires Multiple Sessions
Yes, most cases need 3–6 sessions, spaced 3–4 weeks apart, to enhance hair density and gradually reduce shedding.

Types of Stem Cells Used in Exosome Therapy
Exosomes are primarily derived from different stem cell types, most commonly:

1. Mesenchymal Stem Cells (MSCs)

• Sources: umbilical cord, fat tissue, bone marrow

• Benefits:

  • Reduce scalp inflammation

  • Promote new follicle growth

  • Stimulate proteins that strengthen hair

2. Hair Follicle/Dermal Papilla Stem Cells

• Naturally present in hair roots

• Play a key role in stimulating hair growth and follicle regeneration

Advantages of Different Stem Cells Used in Exosome Therapy

2) Hair Follicle/Dermal Papilla Stem Cells

• Play a key role in the hair growth cycle.

• Help accelerate the growth of weak or thinning hair.

3) Umbilical Stem Cells

• Source: Umbilical cord/placenta of newborns.

• Advantages:

  • Rich in high-growth factors.

  • Strengthen hair follicles and increase collagen in the scalp.

4) Adipose-Derived Stem Cells

• Source: Body fat, easily accessible.

• Advantages:

  • Stimulate blood circulation in the scalp.

  • Reduce hair loss and promote new hair growth.

---

Diagnosis Before Exosome Hair Treatment

Before starting exosome sessions, a precise diagnosis of the scalp and hair is essential for determining suitability and planning the sessions.

1) Scalp and Hair Assessment

• Visual examination of the scalp to evaluate:

  • Hair density in different areas.

  • Presence of thinning or bald spots.

  • Scalp health (dryness, inflammation, dandruff).

• Tools like magnifying cameras or TrichoScan devices may be used for detailed follicle analysis.

2) Determining Hair Loss Type

• Androgenic alopecia (hereditary hair loss): Gradual thinning at the front or crown.

• Stress/nutrition-related hair loss: Typically diffuse and sudden.

• Scalp inflammation or skin disease: Accompanied by itching or redness.

3) Follicle Testing (Optional)

• Some clinics perform hair follicle tests to measure:

  • Ratio of dormant vs. active hairs.

  • Hair thickness and density.

• Helps track exosome treatment progress accurately.

4) Lab Tests if Necessary

• Blood tests may be ordered to check for deficiencies (iron, vitamin D) or hormonal issues affecting hair growth.

5) Treatment Plan

• Number of sessions (usually 3–6).

• Interval between sessions (typically 4–6 weeks).

• Areas requiring more concentrated injections.

• Combining exosomes with other treatments like PRP or fillers if needed.

---

Steps for Exosome Hair Injection

1) Case Assessment

• Doctor examines hair loss severity and identifies areas needing treatment.

2) Scalp Cleaning & Disinfection

• Hair is washed and scalp disinfected for better absorption.

3) Exosome Preparation

• Serum is loaded into a sterile syringe, sometimes mixed with a carrier solution.

4) Application Methods

Method	Description
Direct Injection	Fine needle injected into weak or bald areas
Microneedling / Derma Pen	Tiny channels created to distribute exosomes over the scalp

5) Scalp Massage

• Gentle massage to aid distribution and stimulate blood flow.

Post-Session Instructions

• Avoid washing hair for 24 hours.

• Avoid heat, sauna, or steam.

• No hair coloring or chemical treatments for 1 week.

When Results Appear

• Initial improvement: 2–3 months

• Noticeable density: 4–6 months

---

Benefits of Exosome Therapy for Hair

• Stimulates new follicle growth

• Reduces hereditary and hormonal hair loss

• Improves hair density over time

• Nourishes the scalp and strengthens roots

• Repairs damaged hair from chemicals or heat

• Relatively safe, as it is derived from natural cells

---

Ideal Candidates for Exosome Therapy

• Mild to moderate hair loss: Prevents progression before large bald patches develop

• Weak or damaged hair from dyes/heat: Strengthens roots and reduces breakage

• Scalp problems (dryness, inflammation, dandruff): Restores scalp balance and health

• Hereditary thinning in men and women: Supports density and slows genetic thinning

• Supportive treatment: Can be combined with PRP, mesotherapy, or fillers for faster, clearer results

❌ Not suitable for severe active scalp infections, allergies to any treatment components, or conditions preventing injections.

---

How Exosomes Work in Hair Loss Treatment

• Repair damaged follicles: Rich in growth factors to regenerate damaged cells

• Stimulate new hair production: Enhances communication in dermal papilla cells controlling growth

• Regulate hair growth cycle: Accelerates transition from shedding to growth phase

• Reduce inflammation: Especially important for immune-related hair loss (e.g., alopecia areata)

• Minimize DHT impact: Reduces effect of hormone that shrinks follicles in androgenic alopecia

• Improve hair quality: Rebuilds hair structure and reduces breakage

---

Preparing for Exosome Hair Treatment

1) Medical Consultation

• Dermatologist or hair specialist evaluates hair loss severity and type, determining treatment suitability.

2) Scalp Cleaning

• Wash hair the day before; avoid oils, creams, or styling sprays for better absorption.

3) Temporary Medication Adjustment

• Blood thinners, anti-inflammatories, or high-dose vitamins may need to be paused per doctor’s advice.

4) Avoid Chemical Treatments

• No coloring, keratin, or straightening treatments for 1 week prior.

5) Rest and Good Sleep

• Physical and mental health improve treatment response.

---

Comparing Exosome Therapy, PRP, and Topical Injections

Feature	Exosomes	PRP	Topical Injections
Material	Stem-cell derived growth factors	Patient’s own plasma	Vitamins + growth meds like minoxidil
Method	Precise injection / microneedling	Blood drawn → plasma injected	Ready-made solution injected into scalp
Sessions	3–6 every 4–6 weeks	3–6 every 4–6 weeks	Depends on type, every 2–4 weeks
Duration	30–60 min	30–60 min	15–30 min
Pain	Mild	Mild–moderate	Mild–moderate
Expected Results	Increased density, reduced shedding, healthier scalp	Strengthens follicles, improves growth	Improves scalp, slight reduction in shedding
Results Start	2–3 months	2–4 months	~1–3 sessions
Advantages	Faster & stronger results, ideal for damaged hair	100% natural, from patient’s blood	Lower cost, simpler
Disadvantages	Higher cost, requires skilled practitioner	Best for moderate loss	Weaker results in advanced cases

---

During and After the Session

During:

• Exosomes injected with very fine needles.

• Sensation: slight tingling; session lasts 30–60 minutes.

Immediately After:

• Mild redness or swelling is normal and resolves within hours.

• Avoid washing hair for 24 hours.

• Avoid direct sunlight or high heat.

Expected Changes Over Time:

Timeframe	Expected Change
2–4 weeks	Noticeable reduction in shedding, healthier scalp
2–3 months	New hair growth begins, density increases
4–6 months	Significant improvement in thickness, strength, and shine

Maintenance:

• Follow-up session every 6–12 months may be recommended.

---

Potential Side Effects of Exosome Therapy

Common (usually temporary):

• Scalp redness → resolves same day

• Mild swelling → resolves in 1–2 days

• Minor pain or sensitivity → slight needle prick sensation

• Minor bruising → higher risk if on blood thinners

• Mild itching → due to microneedling stimulation

Rare:

• Severe allergic reaction → very rare, exosomes are cell-free

• Infection → related to poor sterilization or injection technique

Contact Doctor Immediately If:

• Severe or unusual pain, high fever

• Discharge or pus from scalp

• Persistent swelling >3 days

Tips to Maintain Results After Exosome Hair Treatment

1) Choose a Gentle, Sulfate-Free Shampoo

• Avoid SLS and harsh cleansing agents.

• Use a shampoo suitable for sensitive scalps to protect hair and follicles.

2) Minimize Heat Styling

• Hairdryers and straighteners can weaken hair and cause breakage.

• If using heat, always apply a heat protectant beforehand.

3) Avoid Chemical Treatments for a While

• Especially during the first 4–6 weeks after exosome sessions.

• Chemicals from dyes or straightening treatments can stress follicles and reduce results.

4) Maintain a Balanced Diet

• Proteins, iron, zinc, and vitamin D are essential for healthy hair.

• Drink enough water daily to keep your scalp hydrated.

5) Use Serums or Scalp Tonics

• Especially products containing:

  • Peptides

  • Niacinamide

  • Caffeine

• These stimulate blood circulation and help maintain results.

6) Reduce Stress and Mental Pressure

• Psychological stress is a major cause of hair loss.

• Try relaxation exercises, yoga, or light physical activity.

7) Follow-Up Sessions

• Some cases may require a “booster” session every 6 months to maintain hair density and prevent shedding.

8) Avoid Tight Hairstyles

• Tight hair ties can pull on follicles, causing mechanical hair loss.

• Prefer cotton or satin hair ties to reduce friction.

---

Types of Creams and Ointments Used Before Exosome Hair Sessions

1) Topical Anesthetic Creams

• Usually contain Lidocaine or a Lidocaine/Prilocaine blend (e.g., EMLA cream).

• Usage: Applied to the scalp 30–60 minutes before the session under a light covering for absorption.

• Benefit: Reduces pain or tingling during injections, making the session more comfortable.

2) Soothing or Moisturizing Ointments for the Scalp

• Used by the doctor or recommended a few days before the session, especially if the scalp is dry, damaged, or inflamed.

• Important Note: These ointments should be light and free from heavy oils or harsh chemicals, as they may interfere with exosome absorption or cause sensitivity before the injection.