
Lately, the Innofial injection has become one of the most talked-about cosmetic treatments among women on social media. Some people say it brightens the skin and gives an instant glow, while others are hesitant and ask:
"Could it harm my skin? Are there any side effects?"
What most don’t mention is that the results of Innofial depend on the injection technique, skin type, and pre- and post-treatment care. In this Dalily Medical article, we’ll explore whether the Innofial injection can actually affect your skin’s appearance, which cases should avoid it, and share important tips from doctors to achieve the best results safely.
The Innofial injection is one of the latest cosmetic treatments that has recently gained significant popularity. It combines brightening, hydration, and skin rejuvenation in a single session. ✨
The injection contains Hyaluronic Acid, which deeply hydrates the skin, giving it a smooth and firm texture. It also includes other active ingredients like Niacinamide, Tranexamic Acid, and Vitamins C & E, which help to brighten the skin, even out the tone, reduce pigmentation, and at the same time stimulate collagen and elastin production to maintain youthful and radiant skin.
The Innofial solution is injected directly under the skin using a fine syringe or cannula, depending on the area being treated.
Number of sessions: Varies from person to person, typically with at least one week between sessions.
Maintenance: Sessions may be repeated every 3 to 6 months depending on the skin condition to maintain results.
Results are relatively quick:
After the first session, you may notice your skin becoming smoother, brighter, and more radiant.
Full results appear gradually, depending on:
Your skin condition before treatment
The type of Innofial used
The number of sessions completed
In short: initial results are fast, but long-term radiance develops with continued sessions. ✨
Most people need 3 to 5 sessions to achieve optimal results.
Initial improvements appear after the first or second session.
Final results are more noticeable after completing the full course, with a visible difference in tone, smoothness, and radiance.
The procedure is usually mildly uncomfortable, not painful.
A topical anesthetic cream is applied before the session, so you may only feel a quick, light pinch that disappears immediately after the injection.
Sessions are usually scheduled every 2 to 4 weeks, depending on your skin’s condition and response.
After completing the main course, a maintenance session every 3–6 months is recommended to preserve results and radiance.
❌ No. There’s a clear difference:
Innofial: Advanced formula with antioxidants and higher concentration of hyaluronic acid, giving deeper hydration and stronger results.
Mesotherapy: Usually lower concentration, mainly for surface-level nourishment and minor skin brightening.
It’s recommended to avoid makeup for 24 hours after the session.
The skin pores are still open, and early makeup may cause irritation or clog pores.
Avoid direct sun exposure for the first 3 days.
If going outside is necessary, use a light sunscreen without alcohol or fragrances, as UV exposure may cause redness or mild pigmentation.
❌ Absolutely not!
Injections must be performed by a qualified dermatologist or cosmetic physician, as proper knowledge of skin layers and injection points is essential.
Any minor mistake could cause bruising or uneven product distribution.
A proper assessment before the injection is crucial for safety and effectiveness. During this phase, the doctor performs a thorough examination to determine the right type and dosage of Innofial for your skin.
The doctor checks:
Skin type: oily, dry, combination, or sensitive
Existing issues: pigmentation, spots, acne scars, old burns
Previous treatments: fillers, Botox, or other mesotherapy sessions
General health: immune disorders, allergies, pregnancy, or breastfeeding
Some doctors perform a small patch test, especially for first-time users, to ensure there’s no adverse reaction.
Based on evaluation, the doctor sets:
Number of sessions: usually 3–6, depending on the skin
Interval: 2–4 weeks between sessions
Type of Innofial: Classic, H, or Plus (for hydration, brightening, or tightening)
Injection areas: face, neck, or hands
⚠️ Importance of Proper Diagnosis
Skipping assessment may lead to:
Swelling or unwanted inflammation
Uneven distribution of product
Unsatisfactory cosmetic results
Hyaluronic Acid (HA)
Deeply hydrates by attracting water into skin tissues
Smooths fine lines and improves skin texture
Provides instant and gradual plumping effects
Tranexamic Acid (TXA)
Reduces melanin production to fight pigmentation and melasma
Calms inflammation that may cause discoloration
Promotes safe, gradual, and even skin brightening
Niacinamide (Vitamin B3)
Strengthens skin barrier, reduces redness, regulates oil production
Enhances smoothness and skin brightness
Complements tranexamic acid for even tone and gentle brightening
The procedure is completed in four main stages, each contributing to optimal results:
Skin is carefully examined to determine type (dry, oily, sensitive, etc.)
Doctor ensures there are no contraindications (pregnancy, infections, allergies)
Steps:
Cleanse skin with antiseptic solution
Apply topical anesthetic cream to minimize discomfort
Duration: ~15–20 minutes
In this stage, the doctor injects the Innofial solution into the superficial or mid-layers of the skin, depending on your skin condition.
Tools: A very fine needle or a modern mesotherapy device (Derma Gun).
Active ingredients:
Hyaluronic Acid
Tranexamic Acid
Niacinamide
Vitamins for skin nourishment
Areas: Face, neck, or hands.
Duration: Approximately 20–30 minutes.
After the injection, the doctor applies cold compresses or a soothing mask to reduce redness and swelling.
They may also spray a hydrating serum or mineral water mist to calm the skin.
Important Tips:
Avoid touching your face or applying makeup for at least 24 hours.
Initial results appear after the first session.
Full results are usually visible after 3–4 sessions (with a session every 2–3 weeks).
After the main course, a maintenance session every 3–6 months helps preserve radiance.
In addition to the main components (Hyaluronic Acid, Tranexamic Acid, Niacinamide), some types of Innofial or post-treatment skincare products may contain secondary ingredients that enhance effectiveness and prolong results:
Antioxidant Vitamins (C & E):
Preserve skin radiance and fight oxidative stress affecting Hyaluronic Acid.
Improve final results and protect against dryness or new pigmentation.
Moisturizers & Stabilizers:
Ingredients like sterilized water, glycerin, or propanediol help maintain solution stability and absorption.
Additional Ingredients (depending on the brand):
PDRN (Polynucleotides): Stimulates cell regeneration.
Glutathione: Brightens skin and fights oxidation.
Inositol: Improves skin elasticity.
The core Innofial formula always relies on HA + TXA + Niacinamide, with other additives depending on the brand.
Innofial is a comprehensive skin rejuvenation treatment, combining hydration, brightening, and mild skin tightening. Key benefits include:
Deep Skin Hydration:
Hyaluronic Acid retains moisture, making skin soft, elastic, and radiant.
Reduces fine lines and dryness.
Brightening & Even Skin Tone:
Tranexamic Acid and Niacinamide reduce pigmentation, melasma, and freckles.
Result: brighter, smoother, and more uniform skin.
Collagen & Elastin Stimulation:
Active ingredients encourage skin regeneration, improving firmness and youthful appearance.
Reducing Dark Spots & Acne Marks:
Tranexamic Acid calms inflammation and decreases melanin over time.
Immediate Radiance:
The injection boosts circulation and nourishes the skin directly, giving a glowing, fresh look.
Improved Skin Texture & Pores:
Reduces pore size, leaving skin smoother and cleaner.
Cell Renewal & Anti-Aging:
Vitamins and antioxidants fight oxidative stress and early aging, keeping skin youthful longer.
Like any cosmetic injection, some mild temporary effects may appear:
Slight redness or swelling at the injection site
Mild tingling or itching
Small bruises or blue spots, especially in sensitive skin
Slight facial puffiness due to hyaluronic acid absorption
These usually disappear within 24–48 hours. Use a light moisturizer and sunscreen after the session.
Although Innofial is generally safe when performed by a qualified doctor, rare complications may occur if injected incorrectly:
Skin infections or inflammation — caused by unsterilized instruments.
Allergic reactions — e.g., to Tranexamic Acid or Niacinamide, appearing as itching or rash.
Lumps under the skin — from uneven product distribution.
Uneven or unnatural results — from incorrect depth or amount.
Temporary darkening at injection site — usually resolves with soothing creams.
Avoid Innofial if you:
Are pregnant or breastfeeding
Have known allergies to any component
Have active skin infections or open wounds
Take blood-thinning medications (e.g., aspirin, warfarin)
Have immune or uncontrolled chronic diseases
Avoid blood-thinning medications
Skip alcohol and strong stimulants
Stop exfoliating creams or retinol
Avoid sun exposure or tanning sessions
1 Day Before:
Hydrate your skin and drink plenty of water
Get sufficient sleep to reduce swelling
Avoid heavy makeup or thick sunscreen
On the Day of Injection:
Wash your face with a gentle cleanser
Inform the doctor about any medications
Doctor may apply topical anesthetic or cold compress
First 24 Hours:
Avoid touching or pressing your face
Do not wash with hot water; use lukewarm or cold water
Skip makeup or heavy creams, especially with alcohol or fragrance
Use light cold compresses for minor swelling or redness
First 3 Days:
Avoid direct sunlight; if necessary, use light sunscreen
Avoid intense exercise, sauna, or steam
Sleep on your back to prevent facial pressure
After Day 3:
Start a light hydration routine (Aloe Vera gel or soothing cream)
Avoid exfoliants or retinol for at least a week
Drink plenty of water to enhance Hyaluronic Acid effects
Additional Tips:
For minor bruising, use creams containing Arnica or Vitamin K
If swelling or redness persists beyond 2 days, consult your doctor
Results start appearing within 3–5 days and improve further with regular sessions.