

Has your doctor recommended a PET Scan? Or have you heard about it and wondered what makes it so important?
In this comprehensive guide from Dalili Medical, we’ll take you through what a PET Scan is, how it works, its advantages, key medical uses, how it differs from other scans, and how to prepare for it.
PET Scan (Positron Emission Tomography) is an advanced medical imaging technique used to assess the functional activity of tissues and organs — not just their structure.
Unlike traditional imaging like X-rays or CT scans that focus on the shape or size of organs, PET scans show how organs and tissues are working at the cellular level.
It’s widely regarded as one of the most accurate tools in diagnosing complex and chronic conditions such as cancer, heart diseases, and neurological disorders.
Feature | PET Scan | Traditional Imaging (X-ray/CT) |
---|---|---|
Type of Information | Functional (cell activity) | Structural (organ shape/size) |
Cancer Detection | Detects at early stages | Detects in later, visible stages |
Use of Radioactive Tracer | Yes – low-level radioactive substance | Rarely, and in lower doses |
Diagnostic Accuracy | Very high for complex conditions | Moderate to high, depending on the case |
A PET Scan involves injecting a small amount of a radioactive tracer, usually a form of glucose attached to a radioactive isotope.
Active cells (like cancer cells) absorb more glucose. The scanner detects the radiation emitted by these cells and creates detailed images showing areas with abnormal metabolism — areas that may indicate:
Cancerous tumors
Chronic infections or inflammation
Cardiac ischemia (reduced blood flow to the heart)
Brain disorders like Alzheimer’s or epilepsy
Detects and locates tumors
Determines if the cancer has spread (staging)
Monitors effectiveness of chemotherapy or radiation
Detects cancer recurrence after treatment
Measures blood flow to the heart muscle
Detects areas with reduced oxygen supply
Assesses damage after a heart attack
Diagnoses Alzheimer’s disease and other dementias
Identifies epileptic foci (origin of seizures)
Evaluates movement disorders such as Parkinson’s disease
Preparation:
You may be asked to fast for 4 to 6 hours before the scan. Diabetics may need special instructions.
Injection:
A small dose of radioactive glucose is injected intravenously.
Waiting Period:
You’ll wait around 30–60 minutes to allow the tracer to circulate and be absorbed by tissues.
Imaging:
You’ll lie still on a table as the PET scanner rotates around your body capturing detailed images.
Duration:
The whole process typically takes 1 to 2 hours.
✅ Completely painless — you may only feel a small pinch from the injection.
✅ Low radiation exposure — safe for most individuals.
However, always inform your doctor if:
You are pregnant or breastfeeding
You have diabetes (glucose tracer may affect sugar levels)
Resume normal activities immediately unless otherwise instructed.
Drink plenty of water to flush out the tracer from your body.
Results are usually available within 24–48 hours.
Feature | PET Only | PET-CT |
---|---|---|
Purpose | Shows cell activity | Combines function + anatomy |
Detail Level | Functional imaging | Highly detailed and accurate |
Usage | Functional analysis | Widely used in cancer cases |
Detect diseases early, before physical changes occur
Differentiate between benign and malignant tumors
Monitor treatment effectiveness
Non-invasive, safe, and quicker than surgical biopsies
During pregnancy unless absolutely necessary
For young children, unless critically needed
If you have allergies to radioactive materials (very rare)
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PET Scan is one of the most advanced and effective imaging techniques in modern medicine.
It provides functional insights into how your body is working, helping doctors detect disease, guide treatment, and monitor progress with great accuracy.
If your doctor recommends a PET Scan, there’s no need to worry. It’s safe, painless, and could be a key step toward getting the right diagnosis and treatment plan.