Does DHEA-S test for men affect fertility

Feeling low on energy? Noticing a drop in libido or increased hair loss?The issue might be linked to an imbalance in a lesser-known but crucial hormone: DHEA-S (Dehydroepiandrosterone Sulfate).In this article from Dalili Medical, we take you on a complete journey through the DHEA-S test — what it is, why it's ordered, how it relates to your energy and sexual health, and how to interpret your results accurately.

✅ What is DHEA-S?

DHEA-S (Dehydroepiandrosterone Sulfate) is a stable and stored form of the hormone DHEA. It is primarily produced by the adrenal glands and, to a lesser extent, by the ovaries or testes.

DHEA-S acts as a precursor to both male (like testosterone) and female (like estrogen) sex hormones.

❓ Why is the DHEA-S Test Ordered?

Doctors may request a DHEA-S test in various situations for both men and women to assess:

•  Low energy or chronic fatigue

• ⬇️ Decreased libido in men or women

•  Low testosterone levels

•  Muscle mass loss or weakness

• ⚖️ Hormonal imbalances

•  Suspected adrenal gland disorders

•  Masculinization symptoms in women (e.g., excess hair growth, acne)

 How is the DHEA-S Test Performed?

• A blood sample is taken from a vein in the arm.

• No fasting is required.

• The test is best done in the morning when hormone levels are highest.

• Results are usually available within 1–3 days.

 Normal DHEA-S Levels

Values vary based on age and sex, but general reference ranges are:

⚠️ Reference ranges may differ between laboratories.

 Why Is DHEA-S Important?

1. Boosts Physical and Mental Energy
DHEA-S is associated with general vitality and alertness.

2. Enhances Libido
As a testosterone precursor, low DHEA-S can reduce sex drive and erectile function in men, or sexual responsiveness in women.

3. Stress & Aging Protection
It helps balance mood and is sometimes studied for its anti-aging potential.

4. Muscle Support & Fat Metabolism
It plays a role in muscle growth and fat reduction, especially in athletes.

 What Do the Results Mean?

✅ Elevated DHEA-S:

May indicate:

• Adrenal gland overactivity (e.g., Cushing’s syndrome)

• Adrenal or ovarian tumors

• Polycystic ovary syndrome (PCOS) in women

• Use of DHEA supplements or steroids

❌ Low DHEA-S:

Could signal:

• Adrenal insufficiency (Addison’s disease)

• Natural age-related decline

• Chronic stress or depression

• Testicular failure or ovarian dysfunction

 DHEA vs. DHEA-S: What’s the Difference?

⚠️ Can You Take DHEA Supplements?

Yes, but only under strict medical supervision.
While DHEA supplements are used in some countries to improve mood, libido, and energy, they may cause side effects like:

• Acne

• Hormonal imbalance

• Hair loss

• Increased risk of prostate or breast cancer

❓ Frequently Asked Questions

Is DHEA-S important only for women?
No. It’s vital for both men and women, especially in regulating energy, mood, libido, and hormone balance.

Can low DHEA-S cause depression?
Some studies link low DHEA-S with depressive symptoms, particularly in older adults.

When does DHEA-S start to decline?
Typically begins to decrease in the 30s and continues to decline with age.

✅ Article Summary

DHEA-S testing is a valuable tool for evaluating energy levels, libido, adrenal gland function, and sex hormone production. Low levels may explain symptoms like unexplained fatigue, reduced sex drive, or fertility issues.

 If you’re experiencing vague but persistent symptoms, ask your doctor about the DHEA-S test as part of a complete hormonal evaluation.