There are some important nutritional supplements for men, including "Yohimbine", a chemical compound extracted from the bark of the Yohimbe tree. Yohimbine offers many health benefits for men, but what are its potential side effects? Yohimbine is one of the medications that doctors prescribe to treat male sexual dysfunction, such as erectile dysfunction resulting from diabetes, vascular disease, or psychological problems. It has also been promoted as a treatment for losing excess weight, through the Dalili Medical website according to our website.

**Why is Yohimbine used?**

 

Yohimbine is used in many herbal supplements available without a prescription. Yohimbine works by inhibiting alpha-2 adrenergic receptors, which are proteins on nerve cells that interact with norepinephrine. This inhibition reduces the activity of the sympathetic nervous system and increases the activity of the parasympathetic system, which contributes to enhancing blood flow to the penis and helps maintain an erection.

**What is Yohimbe?**

 

Yohimbe is an African tree that grows abundantly in forests, especially in Nigeria, Cameroon, and Congo. This herb is used in sexual treatments, but there are some warnings that studies have shown, as it is considered an unsafe herb. Excessive use of it may lead to serious health problems, such as kidney failure and heart attacks.

**Does Yohimbine Increase Dopamine Levels?**

 

Yes, Yohimbine works to enhance the secretion of dopamine in the brain, and it also affects the neurotransmitter serotonin, which plays an important role as a mediator between nerve cells in regulating various body functions such as sleep, breathing, and others.

**Does Yohimbine Increase Heart Rate?**

 

Yes, research indicates that Yohimbine can lead to an increase in heart rate, depending on the dose used.

**Does Yohimbine Affect Sleep?**

 

Yes, studies conducted on men have shown that Yohimbine may affect sleep and wake cycles.

**Yohimbine and Bodybuilding**

Bodybuilders need nutritional supplements that enhance their muscle density and help them get rid of fat at the same time. The effect of yohimbine extends to reducing fat during exercise, so it is used in weight loss programs in addition to increasing activity and exercise capacity. However, there are not enough studies to prove the effectiveness of yohimbine in increasing muscle density.

**Yohimbine for burning fat** The benefits of yohimbine include its work as an antagonist of alpha 2 receptors, which helps block them in fat cells in the body, facilitating the process of losing fat. In addition, yohimbine contributes to increasing levels of norepinephrine, a neurotransmitter that is considered an effective stimulant for burning fat.

**Benefits of yohimbine for men**

Yohimbine and yohimbine extract can have many potential benefits for men's health, including:

. **Resisting sexual dysfunction**Using yohimbine and yohimbine extract may help combat erectile dysfunction and sexual dysfunction. The potential benefits of yohimbe are due to its components’ ability to:

- Enhance blood flow to the genital area, thanks to yohimbine’s ability to dilate blood vessels.

- Increase nerve activity, which may affect orgasm.

So, using yohimbine may help men: Maintain an erection longer, increase the number of ejaculations, and enhance fertility.

**. Boosting sexual desire in men**The benefits of yohimbine can contribute to improving sexual desire in men. So, if you suffer from low sexual desire or a deterioration in your sex life, using yohimbine may be a suitable option in some cases.

**. Addressing sexual problems associated with antidepressants**Yohimbine can help men address and treat some sexual problems resulting from the use of antidepressants, which is medically known as (antidepressant-induced sexual dysfunction). However, it should be noted that taking certain pharmaceutical forms of yohimbine is what may help overcome these problems, while taking yohimbine bark may not be as effective.

**Anxiety:**There is conflicting evidence about the effectiveness of yohimbine, the active ingredient in yohimbe, in treating anxiety associated with phobias. Some studies suggest that it does not improve anxiety when used with psychotherapy, while other research suggests that it may reduce fear associated with some phobias.

**Depression:**Preliminary research suggests that taking yohimbine, the active ingredient in yohimbe, daily for 10 days may improve symptoms of depression.

**Erectile dysfunction (ED):**There is evidence that yohimbine, the active ingredient in yohimbe, may be helpful in treating erectile dysfunction.

**Exercise performance:**Preliminary research suggests that taking yohimbine, the active ingredient in yohimbe, daily for 21 days may improve exercise performance or help build muscle mass in soccer players.

**Orthostatic hypotension:**Preliminary research suggests that taking a single dose of yohimbine, the active ingredient in yohimbe, may increase blood pressure in people with orthostatic hypotension. However, other studies suggest that it may improve blood pressure in general.

**Sexual problems caused by selective serotonin reuptake inhibitors:** Several studies suggest that yohimbine, the active ingredient in Yohimbe, can help improve sexual problems associated with the use of this class of drugs to treat depression.

**Dry mouth:** Taking yohimbine, the active ingredient in Yohimbe, may help relieve symptoms of dry mouth in people taking antidepressants.

**Major contraindications for using yohimbine**

 

It is essential to take yohimbine supplements or any medications that contain it under medical supervision, especially in the following cases:

- Hypersensitivity to the components of the supplement.

- Before performing anySurgery within a period of not less than 14 days.

- Children under 18 years of age.

- Benign prostatic hyperplasia.

- Kidney or liver disease.

- High blood pressure.

- Heart disease.

- Stomach ulcer.

- Panic attacks.

- Schizophrenia.

**Yohimbe (Yohimbine) Harm**

Yohimbe can cause some side effects when used to relieve the negative sexual effects of antidepressants. Some of these effects include (source):

- Increased anxiety

- Excessive sweating

- Feeling of pain

Excessive use of yohimbe as a treatment for erectile dysfunction may also lead to (source):

- Increased frequency of urination

- High blood pressure

- Mild anxiety

In one study, a young girl who took yohimbe to lose weight experienced some serious side effects, which included (source):

- Alcohol and cocaine-seeking behaviors

- Changes in defensive behavior

**Suicidal tendencies**Another case study looked at two deaths linked to yohimbine, where some of the reported side effects of this drug were monitored. These side effects occurred at varying doses of yohimbine, starting at a dose as low as 0.2 grams. Side effects noted (source):

- Anxiety

- High blood pressure

- Tremors

- Nausea

- Headache

- Skin flushing

- Dissociative reaction, a mental disorder characterized by incoherent thoughts and memories that lead to delusions.

- Drowsiness

- Confusion

- Loss of memory and past memories

- Atrial fibrillation, a condition characterized by an irregular heartbeat that increases the risk of cardiac arrest.

- Loss of consciousness

- Priapism, or prolonged erection not associated with sexual stimulation

- Seizures

- Sinus tachycardia, a common anxiety-related condition characterized by a sudden increase in heart rate as a result of a painful condition.

- Kidney failure

- Death

Cases of allergic reactions to yohimbe bark extract and yohimbine medications have been reported (source). It is advisable to consult a doctor immediately if you experience any of the following severe allergic reactions after taking yohimbine:

- Redness of the skin

- Difficulty breathing

- Swelling of the face, throat or tongue

- Severe dizziness

How can yohimbine be used by men?

 

Yohimbine is available in several forms, including:

1. **Yohimbine tea** To prepare yohimbine tea, boil two cups of water in a pot, and when boiling, add five tablespoons of yohimbine bark powder. Leave the mixture on the fire to boil for 10 minutes, then serve warm.

2. **Yohimbine supplements and medications** It is important to consider some basic points, which are:

**The difference between yohimbine and yohimbine supplements:**

 

Yohimbine is available in different medical forms, which are:

- **Yohimbine medicine:** It is an old medicine that requires a prescription and is used to treat impotence.

- **Yohimbine Supplements:** These are different from the drug yohimbine and are not considered a substitute for it, and may not be as effective as the drug.

While drugs are regulated by the FDA, dietary supplements are not regulated to the same degree, so caution is advised when taking yohimbine supplements.

**Yohimbine Supplements: Do They Really Work?**

 

Before you decide to try any type of yohimbine supplement for men, it is important to know that the supplements available on the market may not always contain the actual yohimbine compound. A study of 49 different types of yohimbine supplements showed that true yohimbine was only found in two of them.

**What precautions should I take before using yohimbine?**

 

Yohimbine is commonly available as a drug on the black market, as well as as an over-the-counter pill, and as an herbal supplement. It is often used as an aphrodisiac or as a weight loss pill. However, research on yohimbine bark extract used in supplements is insufficient, and these supplements are not regulated by the Food and Drug Administration.

Yohimbine extract, which is purified in a lab to become yohimbine hydrochloride, has some research to support its use as a prescription medication for erectile dysfunction. Given the potential side effects of yohimbine, it’s important to take some precautions before using it personally:

Most yohimbine products lack adequate and accurate information on their labels. In a study of 49 brands of yohimbine supplements, only two of them provided accurate information about the amount of yohimbine and its potential side effects. The results also showed that 39% of users were taking either highly processed yohimbine or synthetic yohimbine. Most supplement labels were inaccurate, with yohimbine amounts ranging from 23% to 147% (source). So, you should be aware of this, as these supplements may be ineffective or cause side effects when taken in large amounts.

Yohimbe products can cause negative psychological effects even in healthy individuals, and may worsen psychological conditions in people with known or unknown psychological disorders, such as anxiety (source).

The safety of yohimbe during pregnancy and breastfeeding has not been studied, so pregnant or breastfeeding women are advised to avoid using any products containing yohimbe (source), (source). You should refrain from taking yohimbe if you have kidney or liver problems.

**Yohimbe Drug Interactions**

Yohimbine can interact negatively with some prescription medications. According to a scientific evaluation of the safety of yohimbe, there are some interactions that should be taken into consideration (source), (source).

It is recommended not to take yohimbe supplements with MAO inhibitors.

Yohimbe can also interact with high blood pressure medications.

Additionally, yohimbe may interact with tricyclic antidepressants and phenothiazines, a class of drugs that act as antipsychotics,It helps reduce dopamine overactivity and treat schizophrenia and other psychotic disorders.

It is also important to note that yohimbe interacts with alcohol, which may negatively affect a person’s ability to drive (source).