Xithrone is an effective antibiotic recommended by doctors to treat throat and bronchial infections. This medicine is characterized by the presence of a strong active ingredient that contributes to treating these infections. In Dalili Medical, we will review all the information related to the medicine, including indications and contraindications for its use, in addition to side effects and available alternatives. At the end of the article, we will provide comprehensive answers to the most prominent questions that may come to your mind about this medicine.

What is Xithrone 500?

 

Xithrone 500 is one of the antibiotics used to treat bacterial infections in the throat and bronchial tubes. This medicine contains the active ingredient "azithromycin".

Xithrone is available in the form of tablets containing 500 mg of the active ingredient, and comes in packages containing 3 or 5 tablets. It is also available in the form of syrup, where each 5 ml of the medicine contains 200 mg of the active ingredient.

**Forms and concentrations**

Xithrone is available in pharmacies and hospitals in various forms and concentrations, the most prominent of which are:

- **Xithrone syrup 200 mg/5 ml**: Distilled water is added to it to become a syrup for children, and it is available in two packages, the first weighing 15 grams and the second weighing 25 grams.

- **Xithrone injection 500 mg**: It is given in solution for severe cases and is often used in hospitals.

- **Xithrone tablets 500 mg**: It is intended for adults, and is available in two packages, the first containing 3 tablets and the second containing 5 tablets, and the package is chosen based on the recommendation of the attending physician and the duration of treatment.

Pharmaceutical forms of Xithrone:

There are three pharmaceutical forms of the antibiotic Xithrone:

1. Xithrone tablets with a concentration of 500 mg.

2. Xithrone syrup with a concentration of 200 mg per 5 ml.

3. Xithrone Injection 500 mg for intravenous injection

**Reasons for using Zithrone**

- Respiratory tract infection.

- Acute bronchitis.

- Treatment of bronchitis caused by bacteria.

- Pneumonia.

- Used to treat whooping cough.

- Treating infections of the throat, pharynx and tonsils.

- Recommended to relieve symptoms of severe influenza.

- Recently used in the treatment protocols for the novel coronavirus (Covid-19) infection.

- Helps reduce runny nose and cough.

- Effective in treating sinusitis.

- Reduces infections of the nose and middle ear.

- Prescribed to treat peritoneal membrane infections.

- Used to get rid of infections transmitted through direct sexual contact, such as gonorrhea, chlamydia and syphilis.

- Treating infections caused by Neisseria gonorrhoeae.

- Helps treat bacterial vaginal ulcers.

- Effective in treating urethral disease.

- Infections caused by brown and non-brown cocci that affect the reproductive system, especially in women.

- Cervical infections.

- Treatment of urinary tract infections.

- Urinary tract and bladder infections.

- Relieves prostatitis.

- Enhances prevention of the risk of infection.

Contributes to accelerating the healing of contaminated wounds.

Used to get rid of contaminated skin abscesses or bumps.

Supports the treatment of skin disorders such as acne.

Treats tinea and amoeba.

Treats eye infections.

Used to treat microbacterial infections.

It is prescribed with some other treatments to enhance immunity rates in patients with acquired immunodeficiency syndrome (AIDS).

Helps prevent the risk of malaria.

Supports the treatment of typhoid fever.

** Uses of Zithromax during pregnancy and lactation **

** Pregnancy: ** This medicine is classified as category (B) in terms of safety during pregnancy. Animal studies have not shown any evidence that its use causes fetal malformations. However, its use should be avoided during pregnancy, especially in the first three months, unless necessary as determined by the doctor.

**Breastfeeding:** Azithromycin is used with caution in breastfeeding mothers and under medical supervision, as small amounts of the drug have been found to be excreted in breast milk.

What is the difference between Augmentin and Zithrone?

 

Augmentin contains the antibiotic amoxicillin and clavulanic acid, while Zithrone contains the antibiotic azithromycin.

What is the difference between Zithrone and Zithrocin?

 

They both contain the same active ingredient, azithromycin, and the difference between them lies in the trade name and the manufacturer.

What is the difference between Tavanic and Zithrone?

 

Tavanic contains the antibiotic levofloxacin, while Zithrone contains the antibiotic azithromycin.

What is the difference between Klacid and Zithrone?

 

Clasid contains the antibiotic clarithromycin, while Zithromax contains the antibiotic azithromycin.

Is Zithromax good for treating a cold when taking 3 pills?

 

Colds and flu are caused by viral infections, and antibiotics are ineffective in treating these infections.

Is Zithromax 500 used to treat sore throat?

 

This medicine is effective against the types of bacteria that cause respiratory infections and bacterial sore throat.

Is Zithromax 500 used for children?

 

The medicine can be used in a concentration of 500 mg for children over 12 years of age.

Is Zithromax used to treat acne?

 

A doctor may recommend antibiotics to treat moderate to severe acne. Tetracycline antibiotics (such as minocycline and doxycycline) are usually the first choice, followed by macrolide antibiotics (such as erythromycin and azithromycin).

Is Zithromax the best cold remedy as an antibiotic?

 

Cold is a viral infection, so antibiotics are not recommended to treat it.

Is Xithrone a good antibiotic for sore throat in children?

 

Xithrone can be used as an antibiotic for children in cases of sore throat caused by a bacterial infection.

**Does Xithrone treat coronavirus?**

 

So far, there is noThere is no specific and effective treatment for the Corona virus, but the use of drugs containing the antibiotic azithromycin has been suggested as part of the treatment protocol for Covid-19.

**What are the side effects of Zithromax capsules?**

 

The drug can cause some side effects such as stomach upset, diarrhea, nausea, and vomiting. In some cases, it may lead to changes in hearing, eye problems, muscle weakness, or liver problems.

**Is Zithromax safe during pregnancy?**

 

In general, there are no major concerns about using the drug during pregnancy, but it should be used under medical supervision, especially when the potential benefits are greater than the risks.

**Is Zithromax safe during breastfeeding?**

 

There are not enough studies to confirm the safety or harm of using the drug during breastfeeding.

**Does Zithromax 500 cause diarrhea?**

 

The drug can cause stomach upset or diarrhea as a side effect during the treatment period.

**Does Zithromax cause weight gain?**

 

The drug usually does not cause weight gain, but some studies suggest that changes in gut microbes resulting from excessive use of antibiotics may increase the risk of weight gain and obesity.

**Is it better to take Zithromax before or after food?**

 

It is preferable to take the drug an hour before a meal or two hours after a meal, but it can be taken with food in case of stomach upset.

**What is the best antibiotic to treat viral sore throat?**

 

Antibiotics are not used to treat viral infections, as these drugs target bacteria, not viruses.

**Does Zithromax treat colds?**

 

Colds are viral infections, so it is not preferable to use antibiotics to treat them.

**Does Zithromax cause weight gain?**

 

It usually does not affect weight, but some studies have shown that it may cause changes in the intestines, which may increase the risk of weight gain and obesity.

**Dosage and method of use of Zithrone tablets and injections**

It is important to adhere to the instructions of the attending physician regarding the dosage and method of taking Zithrone tablets, injections or syrup. Here are some general guidelines and precautions regarding the use of the medicine.

**Taking the medicine before or after eating?**

 

Zithrone tablets can be taken with food or at any time without the need to be tied to meals. It is usually recommended to take one tablet daily, so it is important to adhere to a fixed time to take the medicine daily.

**Dosage:**

The usual dose for adults is 500 mg (one tablet) once daily for 3 days, unless otherwise specified by the doctor.

As for children, the usual dose is according to weight, as it is given at a rate of 10 mg per kilogram of the child's weight, once daily for 3 days as well.

The duration of treatment can change based on the doctor's recommendations, and is often extended to 5 days in cases of pneumonia or severe sore throat.

**Damages and side effects**

The side effects of Zithrone vary, as there are some common symptoms, while there are others that are rare. Side effects are expected to be temporary, and if they persist for a long time, it is advisable to consult a doctor.

**Xithrone Tablets Dosage for Adults**

The medicine is usually taken once a day, unless it is used by injection. It is preferable to take the medicine at the same time each day.

The usual dose is 500 mg daily for 3 to 10 days, depending on the type of infection being treated. In some cases, you may need a higher dose of up to 1 gram or 2 grams.

The dose may be lower if you have liver or kidney problems.

Azithromycin is sometimes used long-term to prevent chest infections, especially if you suffer from recurring ones. In this case, it is usually taken three times a week, often on Mondays, Wednesdays and Fridays.

**Xithrone syrup dosage for children**

- **Oral:** On the first day, a dose of 10 to 12 mg per kg of the child's weight is given (usual maximum dose: 500 mg per dose).

- After that, a dose of 5 to 6 mg per kg is given once daily (usual maximum dose: 250 mg per dose) for the rest of the treatment period.

- **Intravenously:** A dose of 10 mg per kg is given once daily, with a maximum dose of 500 mg per dose.

**Xithrone dosage for the elderly**

- The same dose is used as for adults.

**Warning:** It is preferable that the appropriate dose be determined by a specialist doctor or pharmacist.

**Xithrone dosage for pregnant and breastfeeding women**

**Xithrone 500 for pregnant women:** It is usually not recommended for use during pregnancy. However, your doctor may prescribe it if the benefits of taking azithromycin outweigh the potential risks.

**Zithrone and breastfeeding:** In general, it is not recommended to use it during breastfeeding. However, your doctor may decide to prescribe it if the benefits outweigh the risks.

**Contraindications for Xithrone pills**

Antibiotics in general, including Zithrone, are prohibited during pregnancy or breastfeeding, and the dose should only be taken after consulting a specialist doctor.

The drug should not be taken if any allergic symptoms appear, and it is recommended to consult a doctor to determine the appropriate dose or find an alternative that suits the condition.

It is recommended not to use the drug in case of problems with heart rate, blood pressure, or kidney and liver function, except after consulting the attending physician.

It is preferable to take the drug on an empty stomach, but if this causes any intestinal disturbances, it can be taken during a meal.

Common side effects include:

- Abdominal pain

- Diarrhea

- Nausea and vomiting

- Low blood bicarbonate (alkalinity)

- Increase in the number of certain immune cells in the blood, such as monocytes, neutrophils, and white blood cells in general

- Decrease in the number of lymphocytes

Common symptoms in the elderly include:

- Increase in heart rate (increased Q_T wave length in tElectrocardiogram)

For children, common side effects include:

- Abdominal pain

- Headache

- Diarrhea, vomiting and nausea

- Skin rash

Rare side effects associated with Zithromax include:

- Abnormal bleeding from the uterus (through the vagina)

- Abnormal involuntary movements (hyperkinesia)

Unusual sensations in most areas of the body

Loss of appetite and unexplained weight loss

Increased sensitivity

Tension and anxiety without a clear cause

Back pain

Change in the color of stool to dark black

Appearance of bubbles on the skin

Repeated belching

Pain in the chest area

Constipation

Cough

Decrease in the number of red blood cells

Decrease in the number of white blood cells

Weakened sense of taste

Difficulty urinating

Dizziness and constant drowsiness

Dry mouth

Dry skin

Increased or excessive sweating

Abdominal bloating due to accumulation Gases

**Facial swelling**

- Stress and discomfort

- Women feel a heat similar to after menopause

- High temperature in some cases

- Accumulation of fluid in the pleura of the lung

- Increased likelihood of fungal infections

- Headache

- Fever

- Increased saliva secretion

- Disturbances in salt levels in the blood

- Increased platelet count

- Indigestion

- Inflammation of the functional unit of the kidney

- Inflammation of the stomach wall

- Inflammation of the nasal mucosa

- Vaginitis

- Gastroenteritis

- Conjunctivitis

- Itchy skin

- Jaundice

- Joint pain

- Pain in the kidney area

- Weakness of sensation, especially the sense of touch

- Weakness of the sense of smell

- Increased nervousness

- Skin rash

- Ringing in the ears

Sensitivity to sunlight

Pain in the testicles

Change in the color of the tongue

Motion sickness

Vision disturbance

**Precautions and contraindications for using the drug Xithrone**

 

This medicine should not be used by people who are hypersensitive to its components and active ingredients.

It is recommended to avoid using it in cases of jaundice or liver dysfunction.

This medicine should be used with caution in cases of general muscle weakness, and any liver or kidney dysfunction.

It is preferable not to use it by the elderly, as well as pregnant and lactating women, to avoid any side effects.

**Xithrone alternatives available in pharmacies**

There are many medications that contain ingredients similar to Xithrone, making them effective alternatives, including:

- Zithromax

- Azalide

- Zithrocin

- Clindam

- Keflex

- Azithromycin - Capsules and Syrup

- Zerox - Tablets and Syrup

- Zosin - Capsules and Syrup

Warnings when using Zithrone (tablets and syrup)

Caution should be exercised when using Zithrone in some health conditions to avoid side effects. It is necessary to inform the doctor before starting treatment in the following cases:

- If you have diabetes or heart disease.

- If diarrhea occurs as a result of using the drug.

- When taking Ercot or Ergotamine medications.

- The drug should not be used in conjunction with warfarin or any anticoagulant drugs.

- When taking medications to treat heart failure such as digoxin.

- When taking medications to treat acidity or indigestion.

- When taking terfenadine to treat hay fever.

**Warnings when using Zithromax**

Caution should be exercised when using this drug in some health conditions to avoid side effects. It is necessary to inform the doctor before starting to take the drug in the following cases:

- If you have diabetes or heart disease.

- If diarrhea occurs as a result of using the drug.

- When taking Ercot or Ergotamine.

- The drug should not be used in conjunction with warfarin or any anticoagulant drugs.

- When taking medications to treat heart failure such as digoxin.

- Medications used to treat acidity and indigestion.

- When taking terfenadine to treat hay fever.

**Xithrone Interaction with Other Drugs**

Chemical interactions can occur when taking Xithrone, a broad-spectrum antibiotic, with some other drugs, leading to chemical interference. Therefore, it is necessary to inform your doctor when using any of the following drugs:

- Drugs containing ergotamine, used to treat migraines.

- Anticoagulants such as warfarin.

- Treatments containing digoxin, used to treat heart disease.

- Any drugs containing theophylline, used to treat asthma or lung diseases.

- Drugs that regulate heartbeat, such as those containing quinidine.

- Treatments containing cisapride, used to treat stomach problems.

- Drugs containing terfenadine, used to treat allergies.

**Storage conditions for Zithron 500**

The drug should be stored in a place away from heat and moisture.

The drug should be kept out of the reach of children.

The medicine is kept at room temperature, which is between 25 and 30 degrees Celsius.

Trade names for Zithro tablets:

- Azalide

- Rame-Zithro

- Zithrodose