In this article on Dalili Medical website, we will discuss Augmentin, where we will review its composition and indications for use, in addition to the recommended doses and possible side effects. We will also discuss its storage methods and contraindications. It is worth noting that the two active ingredients in Augmentin are amoxicillin and potassium clavulanate, which are the two main elements that affect the effectiveness of the drug.

What is Augmentin?

 

Augmentin is a drug that contains two main components: amoxicillin and clavulanic acid. This combination makes it effective against a wide range of bacteria, more than antibiotics that contain amoxicillin alone. Augmentin is available in several forms, all of which are taken orally:

**Pharmaceutical forms and concentrations:**

 

Augmentin is available in several forms, most of which are taken orally:

- **Augmentin tablets:**

- 250 mg / 125 mg

- 500 mg / 125 mg

- 875 mg / 125 mg

- **Augmentin syrup:**

- (125 mg / 31.25 mg) per 5 ml

- (200 mg / 28.5 mg) per 5 ml

- (250 mg / 62.5 mg) per 5 ml

- (400 mg / 57 mg) per 5 ml

- (600 mg / 42.9 mg) per 5 ml

Intravenous Augmentin injection:

- 1.2 g

- 600 mg

Chewable tablets:

- 200 mg / 28.5 mg

- 400 mg / 57 mg

Augmentin sachets:

- 1 g

Augmentin drops:

- 62.5 mg

**Is it preferable to take Augmentin before or after eating?**

 

It is recommended to take the prescribed dose of the medicine after meals.

**When does Augmentin start to affect the teeth?**

 

The duration of the onset of the effect of Augmentin on the teeth varies depending on the patient's condition, the severity of the infection, and the type of treatment required. In general, the positive effects of Augmentin can appear within hours of taking the first dose, but it may take several days to see a complete improvement in the condition.

Is Augmentin safe during pregnancy?

 

Augmentin is not recommended during pregnancy unless necessary and under the supervision of a specialist doctor.

Drugs are usually classified according to pregnancy categories that indicate how safe they are to use during this period. Augmentin is usually classified in category B, which means that no direct risk to the fetus has been proven in animal studies, but there are not enough studies on pregnant women.

**What is the difference between Augmentin and Curam?**

 

Curam is the same as Augmentin, as they contain the same ingredients and in the same proportions and concentrations. The only difference between them is the manufacturing companies; Curam is produced by Novartis, while Augmentin is produced by GlaxoSmithKline.

**What is the difference between Augmentin and Hi-Biotech?**

 

Hi-Biotech is a well-known alternative to Augmentin. The main difference between them lies in the manufacturing company; Amon produces Hi-Biotech, while GlaxoSmithKline produces Augmentin.

**What is the difference between Clasid and Augmentin?**

 

Both are broad-spectrum antibiotics, but the main difference is that the active ingredient in Clasid is clarithromycin, which has a stronger effect on bacteria than Augmentin. Clasid also does not cause side effects for people with penicillin allergies.

Which is stronger: Augmentin or Flemox?

 

Flemox is definitely the stronger in terms of its effect on humans and its ability to eliminate bacteria, as it contains amoxicillin found in Augmentin in addition to flucloxacillin, which enhances its effectiveness.

What is the difference between Augmentin and Zithromax?

 

Augmentin and Zithromax are two antibacterial drugs, but they contain different active ingredients and are used to treat various types of bacterial infections.

Augmentin is a combination of amoxicillin and clavulanic acid, and is used to treat many infections such as bronchitis, sinusitis, ear infections, skin infections, urinary tract infections, and others.

As for Zithromax, it contains one active ingredient, azithromycin, and is used to treat many infections such as upper and lower respiratory tract infections, urinary tract infections, and skin infections.

Zithromax is characterized by its ability to treat many infections with low doses and for short periods, while Augmentin requires larger doses and a longer treatment period.

Is Augmentin safe?

 

Augmentin is considered safe when used according to the doctor's instructions and adherence to the recommended dose.

What can affect the effectiveness of the antibiotic?

 

There are several factors that may affect the effectiveness of the antibiotic, such as skipping doses or stopping taking it before completing the treatment period.

How long should the antibiotic Augmentin be taken?

 

It should be taken for a period ranging from 5 to 10 days, depending on the severity of the infection.

Is Augmentin used to treat cough?

 

No, Augmentin is not intended to treat cough.

Does Augmentin affect the stomach?

 

Yes, Augmentin may affect the stomach, and may cause side effects such as nausea and diarrhea.

 

Does Augmentin interact with vitamins?

 

There is no accurate information about Augmentin's interactions with vitamins, but it is preferable to consult a doctor if you are taking nutritional supplements.

Is Augmentin used to treat colds?

 

This medicine is not intended to treat viral infections that cause colds and flu. Rather, its use in these cases may lead to the emergence of bacteria that are resistant to antibiotics. Therefore, it is recommended not to use it to treat colds and flu.

Duration of use of the antibiotic Augmentin

 

The duration of use of Augmentin is determined based on each individual's health condition and the doctor's recommendations. The treatment period can range from several weeks to several months, depending on the need and the patient's response to treatment. It is best to consult your doctor for accurate instructions on the appropriate duration of use for your condition.

What should I do if I miss a dose?

 

If you miss a dose, you should take it as soon as possible. But ifIt was only a few hours before the next dose, you can skip the missed dose and continue taking the next dose at the scheduled time.

Never try to take two doses at once, as this may lead to unwanted side effects.

What are the effects of Augmentin on the body?

 

Augmentin can cause some side effects, such as allergic reactions that include itching, swelling of the face, nausea, or diarrhea. These symptoms are limited to people who are allergic to any of the components of this antibiotic.

 

**Augmentin drug concentrations**

 

Augmentin is available in the form of tablets with concentrations of 1000 mg, 625 mg, and 375 mg. Augmentin is also available in the form of a syrup for children with concentrations of: 156 mg/5 ml, 228 mg/5 ml, 312.5 mg/5 ml, and 457 mg/5 ml. In addition, there is Augmentin ES syrup with a concentration of 600 mg, and Augmentin drops for infants with a concentration of 62.5 mg per 1 ml. Augmentin is also available in the form of injections with a concentration of 1.2 mg.

**The difference between Augmentin and Curam**

 

Curam is the same medicine as Augmentin, as they contain the same ingredients in the same proportions and concentrations. The only difference between them is the manufacturing companies; Curam is produced by Novartis, while Augmentin is manufactured by GlaxoSmithKline.

What is the difference between Augmentin and Hi-Biotech?

 

Hi-Biotech is one of the known alternatives to Augmentin, and the only difference between these drugs is the manufacturing company, as Amon is the company that produces Hi-Biotech, while GlaxoSmithKline produces Augmentin.

What is the difference between Klacid and Augmentin?

 

Each of them is a broad-spectrum antibiotic, but the only difference is that the active ingredient in Clasid is clarithromycin, which is one of the substances that has a greater effect than Augmentin on bacteria, and it has no side effects on those who suffer from penicillin allergy.

Which is stronger, Augmentin or Flemox?

 

Of course, Flemox is considered the strongest in terms of its effect on humans and getting rid of bacteria, as it contains amoxicillin found in Augmentin in addition to flucloxacillin, which increases its effect.

Augmentin composition

 

Augmentin and its two active ingredients are amoxicillin and potassium clavulanate. Augmentin tablets are white, oval-shaped tablets. The drug consists of: 

 

Amoxicillin.

 

Potassium clavulanate.

 

Magnesium stearate.

 

Sodium starch glycolate.

 

Colloidal silicon dioxide.

 

Microcrystalline cellulose.

 

Titanium dioxide.

 

Augmentin tablets do not contain sucrose, lactose, gluten or tartrazine.

 

**Indications for use of Augmentin:**

 

. The drug is used to treat all middle ear and tonsil infections, as it completely eliminates the bacteria that cause these infections.

 

. Treats abscesses in the teeth.

 

. It is used to treat bacterial infections in the lower respiratory tract, such as bronchitis and pneumonia.

 

. It treats all bacterial infections in the upper respiratory tract, including sinusitis and nasal passages.

 

. It helps reduce body temperature and treats high temperature (fever) in addition to treating skin infections caused by bacteria.

 

. It contributes to eliminating bacterial infections in the abdomen, including peritonitis.

 

. It is used to treat infections of the reproductive system and urinary tract, especially in cases of recurrent cystitis.

 

**Augmentin Uses**

 

**Augmentin for treating abscesses**

 

Although small boils can heal naturally thanks to the immune system and white blood cells, it is preferable to take Augmentin to get rid of recurring boils.

 

**Augmentin for treating lymphadenitis**

 

Augmentin can be used in this case, as antibiotics that target common bacteria that cause lymphadenitis are usually used, such as amoxicillin, clindamycin, doxycycline, erythromycin, and other medications.

 

**Augmentin for treating fissures**

 

Augmentin is usually not used to treat fissures, as other treatments are more preferred for this condition. Topical treatments such as soothing and anesthetic ointments can be used to relieve pain and irritation, in addition to anti-inflammatory creams to help treat inflammation that may result from fissures.

 

**Augmentin for the treatment of urinary pus**

 

Augmentin is used to treat bacterial infections in the urinary tract, including urinary pus. Augmentin contains a combination of amoxicillin and clavulanic acid, which are antibiotics that work to inhibit the growth of bacteria that cause the infection.

 

**Augmentin for boils**

 

Although small boils can heal on their own thanks to the immune system and white blood cells, it is preferable to take Augmentin to get rid of recurring boils.

 

**Augmentin for the prostate**

 

Augmentin can be relied upon to treat prostatitis, but there are other alternatives that may be more effective, which are prescribed by specialists in this field.

 

**Augmentin for cough**

 

Augmentin may be prescribed by a doctor in cases of recurring cough resulting from bronchitis, for example.

 

**Augmentin Dosage**

 

The Augmentin dose your doctor prescribes will depend on several factors, such as the type and severity of the condition being treated, your age, the type of Augmentin you are taking, and any other medical conditions you may have.

 

The following information provides common or recommended doses, but you should stick to the dose your doctor prescribes. For the concentrations listed below, the first number represents the amount of amoxicillin, and the second number represents the amount of clavulanic acid. It should be noted that the ratio of drug toThe strength of the drug varies between each strength, so one strength cannot be substituted for another. Your doctor will determine the dose that best suits your needs.

 

Augmentin is available in three different strengths:

 

- **Immediate-release tablets**: 250 mg/125 mg, 500 mg/125 mg, 875 mg/125 mg.

 

- **Extended-release tablets**: 1000 mg/62.5 mg.

 

- **Liquid suspension**: 125 mg/31.25 mg per 5 ml, 250 mg/62.5 mg per 5 ml.

 

**Urinary tract infection dosage**

 

Doctors use Augmentin in the form of immediate-release tablets to treat urinary tract infections in adults, where the dosage depends on the severity of the infection and increases as it worsens.

 

The recommended dosage for mild to moderate infections is: one 500 mg tablet every 12 hours, or one 250 mg tablet every 8 hours. For severe infections, the appropriate dose is: one 875 mg tablet every 12 hours, or one 500 mg tablet every 8 hours. The treatment period usually lasts from three to seven days.

 

For sinus infections, doctors prescribe Augmentin to treat sinus symptoms in adults, either in the form of extended-release tablets or immediate-release tablets. The recommended dose varies depending on the severity of symptoms, and should be determined based on the recommendations of a specialist doctor or pharmacist.

**Immediate-release tablets**

 

- **Usual dose:** One 875 mg tablet every 12 hours, or one 500 mg tablet every 8 hours.

 

- **Duration of treatment:** Usually ranges from five to seven days.

 

**Extended-release tablets**

 

- **Usual dose:** Two tablets every 12 hours for 10 days.

 

**Dose for skin infections such as impetigo**

 

**Immediate-release tablets**

 

- **Usual dose:** One 500 mg or 875 mg tablet every 12 hours, or one 250 mg or 500 mg tablet every 8 hours.

 

- **Duration of treatment:** Usually seven days.

 

**Dose for treating ear infections:**

 

- Type of medicine: Immediate-release tablets.

 

- Usual dose: One 875 mg tablet every 12 hours, or one 500 mg tablet every 8 hours.

 

- Duration of treatment: Usually 10 days.

 

**Urinary tract infection treatment dose:**

 

- Usual dose for mild to moderate infections: One 500 mg tablet every 12 hours, or one 250 mg tablet every 8 hours.

 

- Usual doses for severe infections: One 875 mg tablet every 12 hours, or one 500 mg tablet every 8 hours.

 

- Duration of treatment: Usually three to seven days.

 

**Dose for treating skin infections such as impetigo:**

 

- Usual doses: One 500 mg or 875 mg tablet twice daily, or one 250 mg or 500 mg tablet every 8 hours.

- Duration of treatment: Usually seven days.

**Dose for treating ear infections:**

- Usual doses: One 875 mg tablet twice daily, or one 500 mg tablet three times daily.

- Duration of treatment: Usually 10 days.

**Dose for treating pneumonia:**

 

- Usual doses: One 875 mg tablet twice daily, or one 500 mg tablet three times daily.

 

- Duration of treatment: 7 to 10 days.

Recommended dosage for treating respiratory infections, such as pneumonia:

**Immediate-release tablets:**

 

- Usual dosage: One 875 mg tablet every 12 hours, or one 500 mg tablet every 8 hours, for 7 to 10 days.

**Extended-release tablets:**

 

- Usual dosage: Two tablets every 12 hours, for 7 to 10 days.

**Dosage and method of use of Augmentin**

 

1. **For adults**: The medicine is taken every 12 hours for 7 days, and comes in the form of tablets with a concentration of 625 mg or 1000 mg.

 

2. **For children**: Augmentin is used in the form of syrup according to the following:

- For children under one year: The dose is 2-3 times every 8 hours with a concentration of 156 mg.

- For children from 1 to 6 years old: The dose is 2-3 times daily at a concentration of 312 mg. 

- For children over 6 years old: The dose is 3 times daily at a concentration of 457 mg. 

- If the child weighs more than 40 kg, he is given the adult dose.

3. **For infants**: Augmentin is used in the form of oral drops at a concentration of 62.5 mg, and the dose is determined according to the infant's weight using syringes designated for doses.

**Should Augmentin be taken before or after meals?**

 

It is best to take the dose prescribed by the doctor after meals.

**What are the concentrations of Augmentin?**

 

- Tablets with concentrations of 375 mg, 625 mg and 1 gram.

- Syrup for children with concentrations of 156 mg, 312 mg and 457 mg.

- Vial (injection) with concentrations of 600 and 1200 mg (for intravenous injection only).

- Oral drops with a concentration of 62.5 mg per ml.

**Side effects and contraindications for the use of Augmentin:**

 

1. Augmentin may cause some side effects, such as mild gastrointestinal disorders, including abdominal pain, nausea, gas, and diarrhea.

 

2. The patient may feel a mild headache and nausea, but these symptoms do not require stopping the drug until the end of the treatment period, as these symptoms will disappear after the end of the doses.

3. This drug should be avoided in case of allergy to penicillins, and suitable alternatives should be sought.

4. For patients with liver disease, there are no significant risks from using Augmentin, but the doses for kidney patients should be adjusted to match the creatinine clearance rate, so that the dose is 375 mg once daily.

**Augmentin and pregnancy:**

 

There are no negative effects on fetuses according to animal experiments, however, it is preferable for pregnant women to consult their doctor before taking any antibiotics.

**Augmentin and breastfeeding:**

 

The drug is secreted in breast milk but in very small amounts, and these amounts may cause problems for the infant. Therefore, it is advisable to consult a specialist doctor before taking the drug by breastfeeding women.

**AAugmentin and heart health:**

 

Augmentin is a drug that may affect heart health.

**Augmentin and blood pressure:**

 

Augmentin is a drug that significantly affects blood pressure. Therefore, if it is necessary to use this medicine, it is preferable to monitor blood pressure regularly to avoid any risks that the patient may be exposed to.

**Augmentin side effects**

 

You should seek medical help immediately if you experience any signs of an allergic reaction to Augmentin, such as a rash, difficulty breathing, or swelling of the face or throat, in addition to severe skin reactions such as fever, sore throat, burning eyes, skin pain, and the appearance of a red or purple rash with blisters or peeling.

Contact your doctor immediately if any of the following symptoms appear:

- **Liver disorders**: This condition is not common, but it occurs more in the elderly or those who take Augmentin for long periods. The liver usually recovers after stopping the medication, but in some cases the condition may deteriorate and become serious, requiring urgent medical intervention. Symptoms include yellowing of the skin, abdominal pain, and general fatigue.

- **Intestinal inflammation**: Some people who take Augmentin may develop a bacterial infection known as "Clostridium difficile", the symptoms of which appear in the form of severe diarrhea that does not respond to treatment, abdominal pain, nausea, and may be accompanied by the appearance of blood in the stool.

- **Hypersensitivity**: If you are allergic to penicillin and its derivatives and take Augmentin by mistake, you may experience hypersensitivity that appears in the form of a severe rash and swelling.

**Fatigue:** Some people may feel tired, exhausted, and physically weak after taking this medication.

**Fungal infections:** Augmentin can stimulate some fungi, which leads to infections in different areas of the body, especially in the vagina in women.

**Other symptoms:** May include severe stomach pain, or watery or bloody diarrhea, especially if it occurs several months after your last dose.

**Additional signs:** You may have pale or yellow skin, dark urine, fever, confusion, or general weakness.

**Other symptoms:** Loss of appetite, pain in the upper stomach, little or no urination, and easy bruising or bleeding.

**Common side effects:** include nausea, vomiting, and diarrhea, as well as a rash and itching, vaginal itching or increased vaginal discharge.

Bruising.

Itchy skin.

Itchy vagina or genitals.

- Pain during sex.

- Redness of the skin.

- Rash.

- Thick, white vaginal discharge, either odorless or with a slight odor.

- Blood in the urine or cloudy urine.

- Fever.

- Noticeable decrease in the frequency or amount of urination.

- Seizures.

- Swelling in the feet or legs.

- Abdominal or stomach cramps.

- Back, leg, or stomach pain.

- Black, hairy tongue.

- Black stools.

- Bleeding gums.

- Sores, peeling, or erosions on the skin.

- Swelling.

- Blood in the stool.

- Nosebleeding.

- Chest pain.

- Chills.

- Clay-colored stools.

- Cough or hoarseness.

- Skincracks.

Severe watery diarrhea that may be accompanied by blood.

Difficulty breathing.

Difficulty moving.

Difficulty swallowing.

Dizziness.

Rapid heartbeat.

General swelling of the body.

General feeling of tiredness or weakness.

Headache.

Heavy menstrual periods.

Excessive thirst.

Joint or muscle pain.

Noticeable hive-like swelling of the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals.

Loss of appetite.

Low body temperature.

Pain in the lower back or sides.

Muscle stiffness.

Feeling nauseous or vomiting.

Pain, swelling, or redness in the joints.

Red spots on the skin.

Rash.

Red and irritated eyes.

Red and swollen skin.

Sore throat.

Sores or white spots on the lips or inside the mouth.

Swollen glands.

Difficulty breathing with exertion.

Foul-smelling breath.

Unusual bleeding or bruising.

Unexplained weight loss.

Vomiting blood.

Yellowing of the eyes or skin.

Symptoms of an overdose of Augmentin include:

- Abdominal or stomach pain

- Cloudy urine

- Diarrhea

- A noticeable decrease in the number of times you urinate or the amount of urine

- Feeling sleepy

**Contraindications for the use of Augmentin**

 

Augmentin should not be used in some cases, after consulting a specialist doctor and reviewing the medical history or health condition. The doctor determines whether to completely refrain from taking Augmentin or if it is possible to determine a specific dose and not exceed it. The most prominent contraindications for the use of Augmentin include:

- Infants under 3 months of age.

- Breastfeeding mothers.

- Women in the first three months of pregnancy.

- Taking Augmentin with birth control pills.

- Watery diarrhea.

- Kidney failure.

- Patients undergoing dialysis.

- Increased white blood cell count.

- Ulcerative colitis.

- Infection with the human immunodeficiency virus (AIDS).

- Acute lymphoblastic leukemia.

- Taking anticoagulant medications.

**Augmentin overdose**

 

Augmentin overdose can cause symptoms such as vomiting, abdominal pain, diarrhea, and skin rash. Dizziness and interstitial nephritis have also been observed in a small percentage of cases.

When taking large doses, the use of activated carbon and bowel cleansing (such as vomiting) should be considered. Electrolyte levels in the blood should also be corrected if they are abnormal, with the need to monitor urinary excretion, especially in cases of urinary stones

ria).

Hemodialysis is recommended to remove the overdose of the drug, and studies have shown that kidney damage resulting from the use of the drug is reversible.

A study conducted on 51 children in a poison center showed that doses of less than 250 mg/kg of amoxicillin do not cause clinical symptoms and do not require treatment or bowel cleansing.

**Instructions for using Augmentin**

 

This medicine should be taken according to the doctor's instructions, while adhering to all the attached instructions. In general, it is recommended to follow the following instructions:

- It is preferable to take Augmentin at the beginning of a meal to get the best effect.

- The medicine should be taken every 12 hours.

- Do not crush or chew the tablets. Rather, swallow the tablet whole or you can break it in half and take them one by one.

- Make sure to shake the oral suspension (liquid) before measuring the specified amount.

- You should continue taking Augmentin for the entire prescribed period, even if you feel a rapid improvement in symptoms.

- Skipping doses may increase your risk of developing a drug-resistant infection.

- Please note that Augmentin does not affect viral infections such as flu or the common cold.

- Using this medicine may affect the results of some medical tests, so it is best to tell any doctor treating you that you are using Augmentin.