The effect of vitamin D deficiency on bone pain and methods of treatment


Low levels of vitamin D can lead to many physical symptoms, especially on the joints, such as muscle and joint pain, including rheumatoid arthritis pain, which often affects the knees, legs and hips. In this report, "Dalili Medical" reviews the ability of vitamin D to reduce joint problems.

**What are the functions of vitamin D?**

 

1. **Maintaining bone strength:** Having healthy bones helps prevent many diseases, including osteoporosis, a disorder that leads to weak bones, especially in children due to vitamin D deficiency. The body needs vitamin D to enable it to use calcium and phosphorus to build bones. In adults, weak bones can lead to a condition known as osteomalacia.

2. **Calcium absorption:** Vitamin D works with calcium to build bones and maintain their strength and health. Weak bones can lead to fragility and loss of density, which increases the risk of fractures. The vitamin D we get from supplements or from exposure to sunlight is converted into an active form that enhances the effective absorption of calcium from the diet.

3. **Cooperation with the parathyroid gland:** The parathyroid gland constantly works to balance blood calcium levels by communicating with the kidneys, intestines, and skeleton. When there is enough calcium in the diet and enough active vitamin D, calcium is well absorbed and used throughout the body. If calcium intake is insufficient or vitamin D levels are low, the parathyroid glands borrow calcium from the skeleton to keep blood calcium levels within the normal range.

**Does vitamin D deficiency cause joint pain?**

 

Yes, many studies indicate that vitamin D deficiency can lead to joint pain and swelling, given the importance of this vitamin in building and healthy bones, its deficiency negatively affects the joints.

**How ​​does vitamin D deficiency affect the joints?**

 

Several studies have shown the following:

- People with rheumatism have significantly lower vitamin D levels compared to people without the disease.

- People with rheumatism are more likely to have vitamin D deficiency.

- Vitamin D deficiency may be a risk factor for the development of rheumatic diseases and may increase the severity of symptoms.

- Vitamin D supplements are useful for preventing osteoporosis, as rheumatism patients suffer from a higher risk of osteoporotic fractures and suffer from joint pain more, so it is recommended to take nutritional supplements.

**What are the causes of vitamin D deficiency?**

 

There are several factors that lead to low levels of vitamin D in adults, the most prominent of which are:

1. **Aging**: Over time, the skin's ability to produce vitamin D decreases.

2. **Lack of exposure to sunlight**: The body produces vitamin D only when the skin is exposed to sunlight.

3. **Skin color**: Skin color affects the amount of vitamin D produced when exposed to the sun, as light skin contributes to producing larger amounts compared to dark skin.

4. **Vitamin D deficiency in the diet**: Although few foods contain vitamin D naturally, many of them are fortified with it.

5. **Health Conditions**: Certain diseases such as Crohn's disease, celiac disease, ulcerative colitis, cystic fibrosis, obesity, and chronic kidney or liver disease affect the body's ability to absorb or process vitamin D well.

6. **Certain medications and medical procedures**: Such as laxatives, steroids, medications used to treat high cholesterol, seizures or tuberculosis, and intestinal bypass surgery.

It is important to treat vitamin D deficiency, and this requires working with your doctor to develop a safe and effective treatment plan. While reducing exposure to sunlight may cause low levels of vitamin D, increasing exposure to sunlight as a source of this vitamin is not recommended, as this may increase the risk of skin cancer. It is also important to note that consuming excessive amounts of vitamin D can also be harmful to health.

**What are the signs and symptoms of vitamin D deficiency?

 

Many people often do not realize that they are suffering from vitamin D deficiency, as the symptoms are usually not obvious. These symptoms can be difficult to recognize, despite their significant impact on quality of life.

1. **Increased susceptibility to illness and infection**

Vitamin D plays a vital role in boosting your immune system, helping your body fight off pathogenic viruses and bacteria. Vitamin D directly interacts with cells responsible for fighting infection. If you frequently get sick, especially colds or flu, vitamin D deficiency may be a possible cause. Several studies have shown a link between vitamin D deficiency and increased respiratory infections, such as colds, bronchitis, and pneumonia. Research has shown that taking vitamin D supplements at a dose of up to 4,000 IU per day can reduce your risk of respiratory infections.

2. **Feeling tired and fatigued**

There are many reasons for feeling tired, and vitamin D deficiency may be one of them, but it is often overlooked as a possible cause. Studies have shown that very low levels of vitamin D in the blood can lead to fatigue that negatively affects quality of life. Multiple studies have shown that taking vitamin D supplements can reduce the severity of fatigue in people who are severely deficient.

3. **Bone and Back Pain**

Bone pain and lower back pain can be signs of low blood levels of vitamin D. One study of 98 people with lower back pain showed that pain severity was associated with low vitamin D levels. It also showed thatA review of 81 studies found that people with arthritis, muscle pain, and chronic pain tend to have lower levels of vitamin D than healthy people.

4. **Poor wound healing**

Slow wound healing after surgery or injury could be a sign of low vitamin D levels. Studies suggest that vitamin D promotes the production of compounds necessary for the formation of new skin as part of the healing process. Vitamin D’s role in regulating inflammation and fighting infection is also thought to be important for proper healing.

 5- Weak bones

Low bone mineral density indicates a loss of calcium and other minerals, which increases the risk of fractures in older adults, especially women. A large study of more than 1,100 middle-aged postmenopausal women showed a strong association between low vitamin D levels and low bone mineral density.

However, another study showed that women with vitamin D deficiency did not see any improvement in bone mineral density when taking high-dose supplements, even if their blood levels of the mineral improved.

Despite these findings, getting enough vitamin D and keeping blood levels within the ideal range may be an effective strategy to protect bone mass and reduce the risk of fractures.

 6- Hair loss

Hair loss is often thought to be a result of stress, which is a common cause, but when it is severe, it may be due to illness or nutrient deficiency. Research suggests that low levels of vitamin D are associated with alopecia areata, which is a risk factor for this condition.

Alopecia areata is an autoimmune disease characterized by significant hair loss from the head and other parts of the body, and is also associated with bone softening in children due to vitamin D deficiency.

One study of alopecia areata patients showed that low blood levels of vitamin D were associated with more severe hair loss.

 7- Muscle pain

Determining the causes of muscle pain can be difficult, but there is evidence that vitamin D deficiency may be a possible cause of muscle pain in children and adults. In one study, 71% of people with chronic pain were found to be vitamin D deficient.

Studies suggest that vitamin D plays a role in the body’s pain signaling pathways, which may influence chronic pain. A study of 120 children with vitamin D deficiency and growing pains showed that a single dose of the vitamin reduced pain scores by an average of 57%.

 Can vitamin D supplements treat joint pain?

 

One study showed that patients with chronic pain and vitamin D deficiency felt better after taking vitamin D supplements. However, more research is needed to determine whether these supplements benefit all people with chronic joint pain.

 Are there other vitamins and nutrients that can help relieve joint pain?

 

Joint pain is often a sign of inflammation. Other nutrients that may help relieve joint pain include:

- Probiotics, which may be helpful in relieving joint pain caused by autoimmune diseases.

- Omega-3 polyunsaturated fatty acids.

- Calcium.

- Vitamin K.

Researchers have also suggested that following a Mediterranean-style diet may help control pain symptoms and improve overall health. In addition, a diet rich in antioxidants such as fruits, vegetables, nuts, and seeds can promote overall health and reduce the risk of disease.

 Does vitamin D deficiency cause joint pain?

 

Low levels of vitamin D in the body can cause joint pain, and neglecting to treat this deficiency can exacerbate inflammation in the joints.

What is the relationship between sunlight and getting enough vitamin D?

 

Vitamin D is produced when your skin is exposed to sunlight, specifically to ultraviolet B (UV-B) rays emitted by the sun.

The amount of vitamin D your skin can produce depends on several factors, including:

- **Season**: This factor is affected by your geographical location. In some areas, UV-B rays may not reach the Earth for up to six months of the year due to the ozone layer and the angle of the sun.

- **Time of day**: The sun’s rays are strongest between 10 a.m. and 3 p.m. Cloud cover and air pollution also play a role.

- **Geographic location**: Cities closer to the equator have higher levels of UV radiation. UV rays in sunlight are responsible for stimulating the skin to produce vitamin D.

- **Melanin content in the skin**: Melanin is a dark pigment found in the eyes, hair, and skin. The darker your skin, the more sun exposure you need to get enough vitamin D.

How long does it take for vitamin D levels to rise after treatment?

 

Vitamin D3 supplements take up to 24 hours to raise blood levels of vitamin D. However, vitamin D must be converted to its active form, hydroxyvitamin D. Studies have shown that hydroxyvitamin D levels can peak about seven days after taking a high dose of vitamin D3.

In general, it is recommended to check the level of vitamin D in the blood after two to three months of starting to take vitamin D supplements to ensure that its levels are high.

How long does vitamin D deficiency treatment last?

 

The duration of treatment for severe vitamin D deficiency varies depending on the patient's age and the dose used, and is as follows:

**Duration of vitamin D treatment for children**

 

To treat vitamin D deficiency in children between the ages of 1 and 18 years, the following is recommended:

- Take 2000 IU of vitamin D3 daily forThis is not less than six weeks.

- Take 50,000 IU once a week for at least six weeks.

Both methods contribute to raising blood levels of vitamin D to more than 30 nmol/L. After that, a maintenance dose of 600 to 1,000 IU daily should be taken.

**Duration of vitamin D treatment for adults**

 

To treat vitamin D deficiency in adults, it is recommended to take 50,000 IU of vitamin D3 once a week, or the equivalent of 6,000 IU daily.

The dose of 50,000 IU should be continued for 8 weeks, then switch to a maintenance dose of 1,500 to 2,000 IU daily.

**Duration of vitamin D treatment for patients with obesity or malabsorption**

 

The treatment plan for vitamin D deficiency may differ in patients with severe obesity or malabsorption syndromes, or who are taking medications that affect vitamin D metabolism. A higher dose of at least two to three times is suggested.

The recommended dose for treating vitamin D deficiency is 6,000 to 10,000 IU daily, while the maintenance dose is 3,000 to 6,000 IU daily.